Results 81 to 90 of about 1,548,532 (345)

Properties of Mechanically Alloyed W-Ti Materials with Dual Phase Particle Dispersion

open access: yesMetals, 2016
W alloys are currently widely studied materials for their potential application in future fusion reactors. In the presented study, we report on the preparation and properties of mechanically alloyed W-Ti powders compacted by pulsed electric current ...
František Lukáč   +5 more
doaj   +1 more source

New Ti-Alloys and Surface Modifications to Improve the Mechanical Properties and the Biological Response to Orthopedic and Dental Implants: A Review

open access: yesBioMed Research International, 2016
Titanium implants are widely used in the orthopedic and dentistry fields for many decades, for joint arthroplasties, spinal and maxillofacial reconstructions, and dental prostheses.
Yvoni Kirmanidou   +7 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Research status and development trend of high-strength β titanium alloys

open access: yesJournal of Aeronautical Materials, 2020
β-Ti alloys have been used in many military/commercial aircraft since 1950s. Their high specific strength, good corrosion resistance, and high formability meet the special requirement of certain structures.
CHEN Wei, LIU Yunxi, LI Zhiqiang
doaj   +1 more source

Mechanistic origin of high retained strength in refractory BCC high entropy alloys up to 1900K

open access: yes, 2019
The body centered cubic (BCC) high entropy alloys MoNbTaW and MoNbTaVW show exceptional strength retention up to 1900K. The mechanistic origin of the retained strength is unknown yet is crucial for finding the best alloys across the immense space of BCC ...
Curtin, William A., Maresca, Francesco
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Additive manufacturing of dense components in beta‑titanium alloys with crystallographic texture from a mixture of pure metallic element powders

open access: yesMaterials & Design, 2019
The fabrication of dense components composed of Ti-based alloys, i.e., Ti-X (X = Cr, Nb, Mo, Ta) alloys, from a mixture of pure elemental powders was achieved using selective laser melting (SLM) process.
Takeshi Nagase   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Microstructures and Electrochemical Behavior of Ti-Mo Alloys for Biomaterials

open access: yesAdvances in Materials Science and Engineering, 2015
The Ti alloy with 7 wt% Mo revealed a microstructure that contained only the orthorhombic α′′ phase of a fine acicular martensitic structure. The corrosion resistance of the Ti-Mo alloys increased as the Mo content increased.
Back-Sub Sung   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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