Results 101 to 110 of about 1,526,370 (261)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Journal of Materials Research and TechnologyIn this study, nano Ti/AZ31 composites were successfully prepared by powder metallurgy method, and the strength and plasticity of the composites were improved in both directions.
Pengfei Gao +8 more
doaj +1 more source
Reunión del Grupo Técnico Gobierno de TI del 17 de enero 2019
, 2019 Reunión del Grupo Técnico Gobierno de Ti del día 17 de enero 2019. Duración de la sesión: 0 horas 13 minutos.Durante la sesión, se discutieron las primeras actividades para el presente ...
Miembros del Grupo Técnico Gobierno de TI
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Reunión del Grupo Técnico Gobierno de TI del 26 de marzo 2019
, 2019 Reunión del Grupo Técnico Gobierno de Ti del día 26 de marzo 2019. Duración de la sesión: 1 horas 7 minutos.Durante la sesión, Carlos Franco de la ANUIES presentó los resultados de la encuesta sobre Gobierno de TI en las IES de México, así como las ...
Franco, Carlos +1 more
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Fenmo yejin jishuThe (Ti,Nb)C composite carbide particle-reinforced phases were obtained in the Fe-based materials by laser melting deposition method. The microstructure characteristics and interface formation mechanism of the (Ti,Nb)C particle-reinforced Fe-based ...
LI Qingtang, ZHANG Yuchen, WU Hairong
doaj +1 more source
, 2017 The influences of co-deposited Ti particles on corrosion behavior of electrodeposited Ni-Ti coatings were investigated. The co-deposited Ti particles caused the refined crystallite size and random-oriented texture of Ni-Ti coating.
Lianbo Wang +6 more
core +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source