Results 71 to 80 of about 312,235 (310)
Advanced Science, EarlyView.This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Why is there no impact of the host species on the cold tolerance of a generalist parasitoid? [PDF]
, 2017 For generalist parasitoids such as those belonging to the Genus Aphidius, the choice of host species can have profound implications for the emerging parasitoid. Host species is known to affect a variety of life history traits.
Alford, Lucy +4 more
core +3 more sources
Advanced Science, EarlyView.The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher +15 more
wiley +1 more source
Carnets de Géologie, 2010 A pterosaur tibia-fibula is described from Toarcian shales ("Marne de Flize") near the city of Charleville-Mézières (Ardennes, northeastern France). The morphology of this element, especially the reduced fibula partially fused to the tibia, suggests that
Buffetaut Eric +2 more
doaj
Clave de taxones superiores de gorgojos sudamericanos basada en caracteres de los adultos (Coleoptera, Curculionoidea) [PDF]
, 2005 Los gorgojos (Coleoptera: Curculionoidea) de América del Sur se clasifican actualmente en las siguientes familias y subfamilias: Nemonychidae (Rhinorhynchinae), Anthribidae (Anthribinae), Belidae (Belinae y Oxycoryninae), Attelabidae (Attelabinae y ...
Lanteri, Analía Alicia +1 more
core
Growth Plate Injuries of the Lower Extremity: Case Examples and Lessons Learned. [PDF]
, 2018 BackgroundThe presence of growth plates at the ends of long bones makes fracture management in children unique in terms of the potential risk of developing angular deformities and growth arrest.Materials and methodsWe discuss three distinct cases ...
Sabharwal, Samir, Sabharwal, Sanjeev
core +3 more sources
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Fixation of the Anterior Ligament Graft at the Tibial Pole: Biomechanical Analysis of Three Methods [PDF]
Revista Brasileira de OrtopediaObjective Comparative biomechanical analysis of tibial fixation strength for ligament reconstruction with interference screw compared with screw post and washer, and compared with the associated fixation of both methods (hybrid fixation). Method A total
Fernando Pessoa Weiss +5 more
doaj +3 more sources
Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice [PDF]
, 2018 Human osteoarthritis (OA) is detected only at late stages. Male STR/Ort mice develop knee OA spontaneously with known longitudinal trajectory, offering scope to identify OA predisposing factors.
A.A. Pitsillides +57 more
core +4 more sources