Results 131 to 140 of about 123,476 (353)

First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial

open access: yesCancer Communications, EarlyView.
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng   +32 more
wiley   +1 more source

Evaluation of the Epitogen Lyme Detect IgG ELISA: a novel peptide multiplexing approach

open access: yesMicrobiology Spectrum
Lyme Borreliosis (LB), or Lyme disease, is a growing health concern caused by Borrelia burgdorferi sensu lato (Bbsl) bacteria transmitted through tick bites, and untreated cases can lead to severe health complications.
Tiehui Wang   +10 more
doaj   +1 more source

Passive Surveillance in Maine, an Area Emergent for Tick-Borne Diseases [PDF]

open access: hybrid, 2007
Peter W. Rand   +7 more
openalex   +1 more source

Catalytic SuFEx Reactivity of Sulfonimidoyl Fluorides with Functionalized Amines with Automation Applicable Conditions

open access: yesChemistryEurope, EarlyView.
GA: Sulfonimidoyl fluorides react with a diverse set of amines in a HOBt‐catalyzed sulfur(VI) fluorine exchange reaction to access sulfonimidamides, including directly NH‐sulfonimidamides, and in an automated workflow. In addition, SNAr reactivity of 4‐fluoroaryl sulfonimidoyl fluorides is discovered and exploited to prepare complex sulfonimidoyl ...
Dominique Deans   +6 more
wiley   +1 more source

Broad‐Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders

open access: yesChemPhysChem, EarlyView.
Recent advancements in surface plasmon resonance protocols and simulations have enhanced the measurement and prediction of diffusion coefficients (D) for chemical species in microfluidic channels. These developments enable precise determination of D values for molecules ranging from a few angstroms to nanometric aggregates, facilitating detailed ...
Giuseppe Stefano Basile   +4 more
wiley   +1 more source

Identification of novel genes regulating the development of the palate

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

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