Results 21 to 30 of about 31,922 (280)

Incidence and management of Lyme disease: a Scottish general practice retrospective study

BJGP Open
Background: The true burden of Lyme disease in primary care in Scotland is unknown. Epidemiological data are currently based on laboratory-confirmed reports as there is no mandatory reporting of clinical cases.
Sally Mavin, Swapna Guntupalli, Michael Robb   +2 more
doaj   +1 more source

Modern nosoareas of tick-borne encephalitis and tick-borne rickettsiosis in Siberia

Бюллетень сибирской медицины, 2006
Natural centers of tick-borne encephalitis and tick-borne rickettsiosis diseases are distinguished not only by stability and in- creasing level of epidemiological manifestation but also by ability to enlargement of areas.
V. K. Yastrebov
doaj   +1 more source

Predominant risk factors for tick-borne co-infections in hunting dogs from the USA

Parasites & Vectors, 2020
Background Both incidence and geographical range of tick-borne disease has increased across the USA. Similar to people, dogs are hosts for Anaplasma spp., Babesia spp., Ehrlichia spp. and Borrelia burgdorferi.
Kurayi Mahachi, Eric Kontowicz, Bryan Anderson, Angela J. Toepp, Adam Leal Lima, Mandy Larson, Geneva Wilson, Tara Grinnage-Pulley, Carolyne Bennett, Marie Ozanne, Michael Anderson, Hailie Fowler, Molly Parrish, Jill Saucier, Phyllis Tyrrell, Zachary Palmer, Jesse Buch, Ramaswamy Chandrashekar, Breanna Scorza, Grant Brown, Jacob J. Oleson, Christine A. Petersen   +21 more
doaj   +1 more source

Ticking on Pandora’s box: a prospective case-control study into ‘other’ tick-borne diseases

BMC Infectious Diseases, 2021
Background Tick-borne pathogens other than Borrelia burgdorferi sensu lato – the causative agent of Lyme borreliosis – are common in Ixodes ricinus ticks. How often these pathogens cause human disease is unknown. In addition, diagnostic tools to identify
D. Hoornstra, M. G. Harms, S. A. Gauw, A. Wagemakers, T. Azagi, K. Kremer, H. Sprong, C. C. van den Wijngaard, J. W. Hovius   +8 more
doaj   +1 more source

Analysis of Microorganism Diversity in Haemaphysalis longicornis From Shaanxi, China, Based on Metagenomic Sequencing

Frontiers in Genetics, 2021
Ticks are dangerous ectoparasites of humans and animals, as they are important disease vectors and serve as hosts for various microorganisms (including a variety of pathogenic microorganisms).
Runlai Cao, Qiaoyun Ren, Jin Luo, Zhancheng Tian, Wenge Liu, Bo Zhao, Jing Li, Peiwen Diao, Yangchun Tan, Xiaofei Qiu, Gaofeng Zhang, Qilin Wang, Guiquan Guan, Jianxun Luo, Hong Yin, Hong Yin, Guangyuan Liu   +16 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A framework for adaptive surveillance of emerging tick-borne zoonoses

One Health, 2019
Significant global ecological changes continue to drive emergence of tick-borne zoonoses around the world. This poses an important threat to both human and animal health, and highlights the need for surveillance systems that are capable of monitoring ...
Katie M. Clow, Patrick A. Leighton, David L. Pearl, Claire M. Jardine   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Hard tick factors implicated in pathogen transmission. [PDF]

PLoS Neglected Tropical Diseases, 2014
Ticks are the most common arthropod vector, after mosquitoes, and are capable of transmitting the greatest variety of pathogens. For both humans and animals, the worldwide emergence or re-emergence of tick-borne disease is becoming increasingly ...
Xiang Ye Liu, Sarah I Bonnet
doaj   +1 more source