Incidence and management of Lyme disease: a Scottish general practice retrospective study
BJGP OpenBackground: The true burden of Lyme disease in primary care in Scotland is unknown. Epidemiological data are currently based on laboratory-confirmed reports as there is no mandatory reporting of clinical cases.
Sally Mavin +2 more
doaj +1 more source
Modern nosoareas of tick-borne encephalitis and tick-borne rickettsiosis in Siberia
Бюллетень сибирской медицины, 2006 Natural centers of tick-borne encephalitis and tick-borne rickettsiosis diseases are distinguished not only by stability and in- creasing level of epidemiological manifestation but also by ability to enlargement of areas.
V. K. Yastrebov
doaj +1 more source
Predominant risk factors for tick-borne co-infections in hunting dogs from the USA
Parasites & Vectors, 2020 Background Both incidence and geographical range of tick-borne disease has increased across the USA. Similar to people, dogs are hosts for Anaplasma spp., Babesia spp., Ehrlichia spp. and Borrelia burgdorferi.
Kurayi Mahachi +21 more
doaj +1 more source
Emergence of Ixodes scapularis and Borrelia burgdorferi, the Lyme disease vector and agent, in Ohio [PDF]
, 2014 Lyme disease, the most common vector-borne disease in the United States, is caused by a tick-borne infection with Borrelia burgdorferi. Currently, Ohio is considered by the Centers for Disease Control and Prevention (CDC) to be non-endemic for Lyme ...
Armando E. Hoet +6 more
core +2 more sources
Ticking on Pandora’s box: a prospective case-control study into ‘other’ tick-borne diseases
BMC Infectious Diseases, 2021 Background Tick-borne pathogens other than Borrelia burgdorferi sensu lato – the causative agent of Lyme borreliosis – are common in Ixodes ricinus ticks. How often these pathogens cause human disease is unknown. In addition, diagnostic tools to identify
D. Hoornstra +8 more
doaj +1 more source
Frontiers in Genetics, 2021 Ticks are dangerous ectoparasites of humans and animals, as they are important disease vectors and serve as hosts for various microorganisms (including a variety of pathogenic microorganisms).
Runlai Cao +16 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A framework for adaptive surveillance of emerging tick-borne zoonoses
One Health, 2019 Significant global ecological changes continue to drive emergence of tick-borne zoonoses around the world. This poses an important threat to both human and animal health, and highlights the need for surveillance systems that are capable of monitoring ...
Katie M. Clow +3 more
doaj +1 more source
Metagenomic profiling of ticks: Identification of novel rickettsial genomes and detection of tick-borne canine parvovirus [PDF]
, 2019 Background: Across the world, ticks act as vectors of human and animal pathogens. Ticks rely on bacterial endosymbionts, which often share close and complex evolutionary links with tick-borne pathogens.
Abdeen, Ziad +8 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source