Results 81 to 90 of about 166,353 (364)

Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections

Advanced Healthcare Materials, EarlyView.
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic, Evangelos Natsaridis, Timon Flathmann, Daiane P. C. Quadros, Nubia Gogniat, Oya Tagit   +5 more
wiley   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Molecular detection of tick-borne pathogen diversities in ticks from livestock and reptiles along the shores and adjacent islands of lake Victoria and lake Baringo, Kenya [PDF]

, 2017
Tick-borne pathogens (TBPs) are responsible for some of the most serious emerging infectious diseases facing sub-Saharan Africa (SSA) and the rest of the world today (1, 2).
Ajamma, Allsopp, Altschul, Andoh, Bengis, Burgdorfer, Burridge, Collins, Cook, Crowder, Crump, Dantas-Torres, Daszak, de la Fuente, De Sousa, Drummond, Dunster, Fyumagwa, Ghai, Gortazar, Gubbels, Guindon, Hess, Homewood, Horak, Hornok, Kamani, Kariuki, Katoh, Kearse, Kelly, Kiara, Kipkorir, Kock, Kumsa, Latif, Latif, Lwande, Machado-Ferreira, Maina, Maina, Mati, Matsumoto, Maxwell, Mediannikov, Miller, Minakawa, Mokrani, Morzaria, Moumouni, Mukhebi, Mwamuye, Ngumi, Njiiri, Norval, Nowak, Olwoch, Omondi, Onchuru, Oura, Parola, Parola, Punyua, Rosenstein, Rubaire-Akiiki, Saitou, Sang, Sang, Thumbi, Tigoi, Tijsse-Klassen, Tokarz, Trout Fryxell, Uilenberg, Walker, Walker, Walker, Walker, Wanzala, Wanzala, Wen, Wesonga, Wesonga, Whiley, Wiethoelter, Zhu   +85 more
core   +2 more sources

Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers

Advanced Healthcare Materials, EarlyView.
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao, Zheng Zhang, Xincai Wu, Yanwei Chen, Wenjun Li, Jiayan Bao, Xin Zhang, Baoding Chen   +7 more
wiley   +1 more source

Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]

, 2010
Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Brouwer, A., EPIZONE (Funder), Fooks, A.R., Gale, P., Kelly, L., Kosmider, R., Ramnial, V., Snary, E.L.   +7 more
core   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Investigations into the characterization, degradation, and applications of biodegradable polymers by mass spectrometry

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli, Melania Leanza, Marco Rapisarda   +2 more
wiley   +1 more source

Survey of vector-borne agents in feral cats and first report of Babesia gibsoni in cats on St Kitts, West Indies [PDF]

, 2017
Background: As there is little data on vector-borne diseases of cats in the Caribbean region and even around the world, we tested feral cats from St Kitts by PCR to detect infections with Babesia, Ehrlichia and spotted fever group Rickettsia (SFGR) and
Branford, Gillian Carmichael, Huang, Ke, Kelly, Patrick john, Köster, Liza, Li, Jing, Marchi, Silvia, Vandenplas, Michel, Wang, Chengming, Zhang, Jilei   +8 more
core   +1 more source

Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing

Advanced Materials, EarlyView.
Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko, Deep Sekhar Biswas, Pascal Didier   +2 more
wiley   +1 more source

Insights into the development of Ixodes scapularis: a resource for research on a medically important tick species [PDF]

, 2017
Ticks (Acari: Ixodida) are arthropod ectoparasites dependent on a bloodmeal from a vertebrate host at each developmental stage for completion of their life cycle.
Coburn, Lisa A., Fuente, José de la, Kocan, Katherine M.   +2 more
core   +1 more source