Results 31 to 40 of about 39,930 (314)

Nucleoside Inhibitors of Tick-Borne Encephalitis Virus [PDF]

Antimicrobial Agents and Chemotherapy, 2015
ABSTRACT Tick-borne encephalitis virus (TBEV) is a leading cause of human neuroinfections in Europe and Northeast Asia. There are no antiviral therapies for treating TBEV infection. A series of nucleoside analogues was tested for the ability to inhibit the replication of TBEV in porcine kidney cells and human neuroblastoma cells.
Eyer, Luděk, Valdés, James J., Gil, Victor A., Nencka, Radim, Hřebabecký, Hubert, Šála, Michal, Salát, Jiří, Černý, Jiří, Palus, Martin, De Clercq, Erik, Růžek, Daniel   +10 more
openaire   +2 more sources

T Cells in Tick-Borne Flavivirus Encephalitis: A Review of Current Paradigms in Protection and Disease Pathology

Viruses, 2023
The family Flaviviridae is comprised of a diverse group of arthropod-borne viruses that are the etiological agents of globally relevant diseases in humans.
E. Taylor Stone, Amelia K. Pinto
doaj   +1 more source

Analysis of synonymous codon usage bias, nucleotide and amino acid composition in 13 species of Flaviviridae [PDF]

Journal of Cell and Molecular Research, 2011
Flaviviridae are viruses that cause several diseases including Dengue fever, Japanese encephalitis, Murray Valley encephalitis, Tick-borne encephalitis, West Nile encephalitis, Yellow fever and Hepatitis C Virus Infection.
Fatemeh Moosawi, Hassan Mohabatkar, Sasan Mohsenzadeh   +2 more
doaj   +1 more source

Clinical and Laboratory Characteristics and Outcome of Illness Caused by Tick-Borne Encephalitis Virus without Central Nervous System Involvement

Emerging Infectious Diseases, 2022
Illness progressed to encephalitis in 84% of patients within 18 days after defervescence.
Petra Bogovič, Andrej Kastrin, S. Lotrič-Furlan, K. Ogrinc, T. A. Županc, M. Korva, N. Knap, F. Strle   +7 more
semanticscholar   +1 more source

Immunoinformatics and Immunogenetics-Based Design of Immunogenic Peptides Vaccine against the Emerging Tick-Borne Encephalitis Virus (TBEV) and Its Validation through In Silico Cloning and Immune Simulation

Vaccines, 2021
Tick-borne encephalitis virus (TBEV), belonging to the Flaviviridae family, is transmitted to humans via infected tick bites, leading to serious neurological complications and, in some cases, death. The available vaccines against the TBEV are reported to
Muhammad Suleman, M. T. ul Qamar, Kiran, Samreen Rasool, A. Rasool, Aqel Albutti, Noorah Alsowayeh, A. S. Alwashmi, M. Aljasir, Sajjad Ahmad, Z. Hussain, M. Rizwan, Syed Shujait Ali, Abbas Saleem Khan, Dongqing Wei   +14 more
semanticscholar   +1 more source

The Role of IFITM Proteins in Tick-Borne Encephalitis Virus Infection

Journal of Virology, 2021
TBEV infection may result in encephalitis, chronic illness, or death. TBEV is endemic in northern Asia and Europe; however, due to climate change, new centers of endemicity have arisen.
A. Chmielewska, Maria Gómez-Herranz, Paulina Gach, M. Nekulová, Małgorzata A. Bagnucka, A. Lipińska, M. Rychłowski, Weronika Hoffmann, E. Król, B. Vojtěšek, Richard Sloan, K. Bieńkowska-Szewczyk, T. Hupp, K. Ball   +13 more
semanticscholar   +1 more source

Evolutionary traits of Tick-borne encephalitis virus: Pervasive non-coding RNA structure conservation and molecular epidemiology

bioRxiv, 2021
Tick-borne encephalitis virus (TBEV) is the etiological agent of tick-borne encephalitis, an infectious disease of the central nervous system that is often associated with severe sequelae in humans. While TBEV is typically classified into three subtypes,
Lena S. Kutschera, Michael T. Wolfinger
semanticscholar   +1 more source

Risk of infections transmitted by arthropods and rodents in forestry workers. [PDF]

, 1994
One hundred and fifty-one forestry workers and 151 matched office clerks were compared as to the presence of antibodies against Borelia burgdorferi, tick-borne encephalitis virus, Puumalavirus and lymphocytic choriomeningitis virus.
A. D. M. E. Osterhaus, A. W. Moll van Charante, AW Moll van Charante, B Ma, B Niklasson, BS Schwartz, CF Stanford, E Schmutzhard, EB Holmgren, J Groen, J. Groen, JE Childs, JMG Jordans, K Hansen, M Nuti, World Health Organisation, WR Rahn   +16 more
core   +2 more sources

Tick-Borne Encephalitis Virus: A Quest for Better Vaccines against a Virus on the Rise

Vaccines, 2020
Tick-borne encephalitis virus (TBEV), a member of the family Flaviviridae, is one of the most important tick-transmitted viruses in Europe and Asia.
Mareike Kubinski, Jana Beicht, T. Gerlach, A. Volz, G. Sutter, G. Rimmelzwaan   +5 more
semanticscholar   +1 more source

Tick-Borne Encephalitis Virus Seropositivity among Tick Infested Individuals in Serbia

Pathogens, 2021
Tick-borne encephalitis (TBE), caused by the TBE virus (TBEV), is a life-threatening disease with clinical symptoms ranging from non-specific to severe inflammation of the central nervous system.
Pavle Banović, D. Obregón, D. Mijatović, Verica Simin, S. Stankov, Zorana Budakov-Obradović, Nevenka Bujandrić, Jasmina Grujić, S. Sevic, V. Turkulov, A. A. Díaz-Sánchez, A. Cabezas-Cruz   +11 more
semanticscholar   +1 more source