Results 51 to 60 of about 19,808 (214)

Impact of tick-borne pathogens on the health risk of soldiers

Annals of Agricultural and Environmental Medicine, 2023
Vector diseases are common in Europe, including Poland. Every year, 77,000 Europeans are infected with transmissive diseases as a result of contact with infected vectors. In Poland, ticks are vectors of great epidemiological importance. The most important etiological factors causing disease in humans and transmitted by ticks include bacteria of the ...
Anna Borecka, Małgorzata Szczypek, Agata Pabin, Krzysztof Kowalczuk, Ewelina Maculewicz   +4 more
openaire   +2 more sources

Innovative approaches for the control of ticks and tick-borne diseases

Ticks and Tick-Borne Diseases, 2023
Ticks and tick-borne diseases constitute a major threat for human and animal health worldwide. Vaccines for the control of tick infestations and transmitted pathogens still represents a challenge for science and health.
José de la Fuente, Lorena Mazuecos, Marinela Contreras   +2 more
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source

Tick-Borne Co-Infections: Challenges in Molecular and Serologic Diagnoses

Pathogens, 2023
Co-infections are a poorly understood aspect of tick-borne diseases. In the United States alone, nineteen different tick-borne pathogens have been identified.
Santiago Sanchez-Vicente, Rafal Tokarz
doaj   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Survey of ticks and tick-borne pathogens in wild chimpanzee habitat in Western Uganda

Parasites & Vectors, 2023
Background Ticks and tick-borne pathogens significantly impact both human and animal health and therefore are of major concern to the scientific community. Knowledge of tick-borne pathogens is crucial for prescription of mitigation measures.
Camille Lacroux, Sarah Bonnet, Emmanuelle Pouydebat, Marie Buysse, Nil Rahola, Sabine Rakotobe, John-Paul Okimat, Rachid Koual, Edward Asalu, Sabrina Krief, Olivier Duron   +10 more
doaj   +1 more source

Prevalence of Tick Borne Pathogens in Horses from Italy

Journal of Veterinary Medical Science, 2013
In order to investigate the prevalence of tick-borne diseases, equine piroplasmosis, equine granulocytic anaplasmosis and Lyme borreliosis in Central Italy, blood samples from 300 horses were analyzed for the presence of antibodies against Babesia caballi, Theileria equi, Anaplasma phagocytophilum and Borrelia burgdorferi using the IFAT.
Laus F., VERONESI, FABRIZIA, PASSAMONTI, Fabrizio, Paggi E., Cerquetella M., Hyatt D., Tesei B., PIERGILI FIORETTI, Daniela   +7 more
openaire   +5 more sources

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Epidemiological survey of ticks and tick-borne pathogens in pet dogs in south-eastern China

Parasite, 2017
To understand the epidemiology of tick infestation and tick-borne diseases in pet dogs in south-eastern China and to develop a reference for their prevention and treatment, we collected 1550 ticks parasitizing 562 dogs in 122 veterinary clinics from 20 ...
Zhang Jianwei, Liu Qingbiao, Wang Demou, Li Wanmeng, Beugnet Frédéric, Zhou Jinlin   +5 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source