Results 171 to 180 of about 9,864,889 (296)

Internal Resonance Mismatch‐Controlled Dissipative Bistability Collapse in Coupled Micromechanical Oscillators

Advanced Science, EarlyView.
This paper reveals internal resonance mismatch‐controlled dissipative bistability collapse in a coupled micromechanical resonator. Tuning δIR changes both internal‐mode amplitude and phase‐dependent feedback. For negative mismatch, Duffing bistability survives.
Jianlin Chen, Xin Zhou, Takashiro Tsukamoto, Nan Wang, Shuji Tanaka   +4 more
wiley   +1 more source

The BiteBarrier perimeter: A passive spatial device for tick control and bite prevention. [PDF]

Curr Res Parasitol Vector Borne Dis
Murgia MV, Widder L, Hill CA.
europepmc   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Does fluralaner (Exzolt^® 5%) affect the enzootic stability of tick fever in beef calves subjected to strategic tick control in a tropical region? [PDF]

Parasit Vectors
de Aquino LM, de Morais IML, Salvador VF, Leal LLLL, Ribeiro NB, Heller LM, Tamiozo GL, Bittencourt RBM, de Lima NJ, Ferreira LL, de Castro Rodrigues D, Strydom T, Torres S, Soares VE, de Oliveira Monteiro CM, da Silva Krawczak F, Lopes WDZ.   +16 more
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Aurora kinase as a putative target to tick control. [PDF]

Parasitology
Moraes B, Gomes H, Saramago L, Braz V, Parizi LF, Braz G, da Silva Vaz I, Logullo C, Moraes J.   +8 more
europepmc   +1 more source

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

Advanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao, Jian Zhang, Qi Qian, Min Jiang, Yu Liu, Yan Geng, Nan Cui, Qi Guo, Jie Guo   +8 more
wiley   +1 more source

A scoping review of applied tick control research in North America: funding, implementation, and advancement. [PDF]

J Med Entomol
Lehane Á, Mader EM, Poggi JD, McCoy KD, Gruntmeir J, Weldon CT.   +5 more
europepmc   +1 more source

Maine Forest Tick Survey Website

Maine has fifteen recorded species of ticks, though the predominant number of tick-borne illnesses are attributed to the black-legged tick (Ixodes scapularis), commonly called the deer tick.
University of Maine, Maine Forest Tick Survey   +1 more
core  

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source