Results 221 to 230 of about 296,107 (354)

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Modeling platform to assess the effectiveness of single and integrated Ixodes scapularis tick control methods. [PDF]

Parasit Vectors
Ruiz-Carrascal D, Bastard J, Williams SC, Diuk-Wasser M.   +3 more
europepmc   +1 more source

Mediterranean Theileriosis and Other Tick Transmitted Piroplasmoses in Cattle in Minorca (Balearic Islands, Spain): the Effect of Tick Control on Prevalence Levels Analyzed by Reverse Line Blot (Rlb) Macroarrays

, 2009
S. Almerı́a, Yolanda Delgado-Neira, Carles Adelantado, Marian Huguet, Joan Vinent, Antoni Nicolàs   +5 more
openalex   +2 more sources

Screening of Acaricides for Control of One-Host Ticks, 1982 [PDF]

, 1983
R. O. Drummond
openalex   +1 more source

Epidemiology of tick-borne pathogens of cattle and tick control practices in coastal Kenya

, 2022
Joseph Wang’ang’a Oundo, Daniel Masiga, Quirine A. ten Bosch, Jandouwe Villinger, Constantianus J. M. Koenraadt, Shewit Kalayou   +5 more
openalex   +2 more sources

Integrated tick and tick-borne disease control trials in crossbred dairy cattle in Malawi [PDF]

, 1996
Chamambala, K. E., Kafuwa, P. T., Lawrence, J. A., Mfitilodze, M. W., Musisi, F. L., Tjørnehøj, Kirsten, Whiteland, A. P.   +6 more
core   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

Advanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi, Mohammad Mahdi Hosseini, Ahmadreza Argha, Roxana Zahedi, Nigel H. Lovell, Hamid Alinejad‐Rokny   +5 more
wiley   +1 more source

Release the hens: a study on the complexities of guinea fowl as tick control. [PDF]

J Med Entomol
White AL, Cumbie A, Brinkerhoff RJ, Hynes WL, Gaff HD.   +4 more
europepmc   +1 more source

Distribution of Ionomotive Pumps and Control of Malpighian Tubule Secretion By Cyclic Nucleotides in the Black-Legged Tick, Ixodes Scapularis

, 2017
Melanie Blanche Paez
openalex   +1 more source

Ticks: biology, disease and control [PDF]

Parasitology, 2004
A. S. BOWMAN, P. A. NUTTALL, L. H. CHAPPELL   +2 more
openaire   +1 more source