Results 221 to 230 of about 82,246 (321)

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

open access: yesAdvanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin   +7 more
wiley   +1 more source

Fourteen anti-tick vaccine targets are variably conserved in cattle fever ticks. [PDF]

open access: yesParasit Vectors
Busch JD   +18 more
europepmc   +1 more source

A new approach to development of live vaccine against tick-borne encephalitis [PDF]

open access: bronze, 1969
A. A. Smorodintsev   +3 more
openalex   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

open access: yesAdvanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi   +12 more
wiley   +1 more source

Climate-driven variation in the phenology of juvenile Ixodes pacificus on lizard hosts. [PDF]

open access: yesParasit Vectors
Sambado S   +9 more
europepmc   +1 more source

ALKBH3‐Mediated M1A Demethylation of METTL3 Endows Pathological Fibrosis:Interplay Between M1A and M6A RNA Methylation

open access: yesAdvanced Science, EarlyView.
RNA modification is crucial in fibrosis diseases, but the role of m1A modification remains elusive. This study reveals that ALKBH3, an m1A demethylase, drives skin fibrosis by reshaping m6A RNA modification and stabilizing COL1A1 and FN1 mRNAs through METTL3, uncovering a crosstalk between m1A and m6A methylation in pathological events.
Liying Tu   +9 more
wiley   +1 more source

Analysis of ticks (Acari: Ixodida) and associated microorganisms collected on the North Sea Island of Heligoland. [PDF]

open access: yesParasitol Res
Rollins RE   +5 more
europepmc   +1 more source

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