Results 61 to 70 of about 280,062 (388)

Tick cell lines: tools for tick and tick-borne disease research [PDF]

Trends in Parasitology, 2007
Over 40 cell lines are currently available from 13 ixodid and one argasid tick species. The successful isolation and propagation of several economically important tick-borne pathogens in tick cell lines has created a useful model to study interactions between tick cells and these viral and bacterial disease agents.
Frans Jongejan, Frans Jongejan, Lesley Bell-Sakyi, Ernest A. Gould, Erich Zweygarth, Edmour F. Blouin   +5 more
openaire   +5 more sources

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Molecular Diversity of Hard Tick Species from Selected Areas of a Wildlife-Livestock Interface Ecosystem at Mikumi National Park, Morogoro Region, Tanzania

Veterinary Sciences, 2021
Ticks are one of the most important arthropod vectors and reservoirs as they harbor a wide variety of viruses, bacteria, fungi, protozoa, and nematodes, which can cause diseases in human and livestock.
Donath Damian, Modester Damas, Jonas Johansson Wensman, Mikael Berg   +3 more
doaj   +1 more source

Modeling the effects of variable feeding patterns of larval ticks on the transmission of Borrelia lusitaniae and Borrelia afzelii [PDF]

, 2017
Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving Ixodes ricinus
Bertolotti, Luigi, Ferreri, Luca, Giacobini, Mario, Mannelli, Alessandro, Perazzo, Silvia, Venturino, Ezio   +5 more
core   +2 more sources

Predicting the potential distribution of Amblyomma americanum (Acari: Ixodidae) infestation in New Zealand, using maximum entropy-based ecological niche modelling [PDF]

, 2020
Publishe
Ganta, RR, Heath, ACG, Lawrence, KE, Peterson, AT, Pomroy, WE, Raghavan, RK   +5 more
core   +1 more source

Imported Hyalomma ticks in Germany in 2018

Parasites & Vectors, 2019
Hyalomma marginatum and Hyalomma rufipes are two-host tick species, which are mainly distributed in southern Europe, Africa and middle-eastern Asia. They are well-known vectors of Crimean Congo hemorrhagic fever (CCHF) virus and other viruses as well as ...
L. Chitimia-Dobler, Sabine Schaper, R. Rieß, Karin Bitterwolf, D. Frangoulidis, M. Bestehorn, A. Springer, R. Oehme, Marco Drehmann, A. Lindau, U. Mackenstedt, C. Strube, G. Dobler   +12 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Geospatial Analysis of Rickettsial Species [PDF]

, 2019
Rickettsia species are obligate intracellular, arthropod-borne bacteria with a potential to cause multiple diseases including Rocky Mountain spotted fever (RMSF).
Frank, Amy
core   +3 more sources

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission [PDF]

, 2016
BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa.
A Musoke, A Musoke, AR Trimnell, AR Trimnell, AR Walker, AS Bowman, AS Young, AS Young, B Minjauw, C Almazán, C Almazán, C Almazán, C Almazán, CA Ferreira, Cassandra L. Olds, CL Schwartzkoff, Claudia Daubenberger, David O. Odongo, DO Odongo, DO Odongo, G Büscher, GC Paesen, GJ Rowlands, Glen A. Scoles, H Ochanda, I Couillin, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Katende, JD Hunt, JD Hunt, JG Valenzuela, JH Pruett, JM Ribeiro, JO Adejinmi, K Bailey, KM Kocan, M Labuda, M Saimo, M Shakya, MP Szabó, NA Steen, NH Ogden, O Merino, O Merino, P Willadsen, P Willadsen, P Willadsen, PG Toye, R Bishop, R Bishop, RA Skilton, RAI Norval, RC Galindo, Richard Bishop, S Havlíková, SK Wikel, Stephen Mwaura, T Bazarusanga, T Schetters, TT Dolan, V Nene, Z Zivkovic   +65 more
core   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source