Results 101 to 110 of about 17,756 (301)

Clopidogrel-Induced Neutropenia after Coronary Stenting: Is Cilostazol a Good Alternative?

open access: yesInternational Journal of Vascular Medicine, 2011
Dual antiplatelet therapy with aspirin plus thienopyridines has become the standard treatment of patients undergoing coronary stenting. Clopidogrel has mostly replaced the use of ticlopidine due to its more favourable adverse event profile. However, also
Massimo Montalto   +7 more
doaj   +1 more source

Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]

open access: yes, 2018
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core   +1 more source

Anti-platelet therapy: ADP receptor antagonists. [PDF]

open access: yes, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD
core   +2 more sources

Role of ticlopidine for prevention of stroke. [PDF]

open access: yesStroke, 1992
Ticlopidine, an antiplatelet agent with a unique mechanism of action, is now available for clinical use in the United States and Canada. Recently two large randomized trials demonstrated that ticlopidine can reduce the risk of subsequent stroke in patients presenting with a transient ischemic attack or stroke. One study found that ticlopidine
openaire   +2 more sources

Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel .

open access: yesBiochemistry, 2010
Prior X-ray crystal structures of rabbit cytochrome P450 2B4 (2B4) in complexes with various imidazoles have demonstrated markedly different enzyme conformations depending on the size of the inhibitor occupying the active site.
S. Gay   +7 more
semanticscholar   +1 more source

Dataset of endo- and xenobiotic inhibition of CYP2B6: Comparison to CYP3A4

open access: yesData in Brief, 2022
Cytochrome P450 2B6 (CYP2B6) is a human enzyme important in chemical detoxification, steroid and fatty acid metabolism that is primarily hepatic. Therefore, induction or inhibition of CYP2B6 may perturb endo- and xenobiotic metabolism and cause adverse ...
Emily M. Olack   +2 more
doaj  

Aortic thrombus in a patient with myeloproliferative thrombocytosis, successfully treated by pharmaceutical therapy: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Thrombosis in myeloproliferative thrombocytosis occurs usually in the microvessels and medium-sized arteries and veins and only rarely in the aorta. Aortic thrombosis is usually treated with thrombectomy.
Imai Norikazu   +4 more
doaj   +1 more source

The long and winding road: the management of Acute Coronary Syndromes in Malta [PDF]

open access: yes, 2003
The treatment of acute coronary syndromes in Malta has been revolutionized over the past decade by the introduction of the catheterization laboratory. With the set-up of on-call cardiac invasive teams for primary percutaneous coronary interventions in ST-
Xuereb, Mariosa, Xuereb, Robert G.
core  

A better effect of cilostazol for reducing in-stent restenosis after femoropopliteal artery stent placement in comparison with ticlopidine

open access: yesMedical Devices: Evidence and Research, 2011
Ichiro Ikushima1, Kazuchika Yonenaga1, Hironao Iwakiri2, Hideki Nagoshi2, Haruhito Kumagai2, Yasuyuki Yamashita31Department of Radiology, 2Department of Cardiology, Miyakonojo Medical Association Hospital, Miyakonojo, Japan; 3Department of Diagnostic ...
Ikushima I   +5 more
doaj  

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