Results 141 to 150 of about 16,218 (220)

Ultrasound of the inferior vena cava for fluid therapy decisions: Strengths, limitations, and an integrated approach. [PDF]

J Int Med Res
Guo X, Tang M, Jiang X, Lin J, Chen W, Song Y.   +5 more
europepmc   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice. [PDF]

Psychopharmacology (Berl)
Watkins JM, Hahn R, Dempsey M, Hohmann AG.   +3 more
europepmc   +1 more source

Safer prehospital anaesthesia: updated guidelines from the Association of Anaesthetists

Anaesthesia, EarlyView.
Summary Introduction Prehospital emergency anaesthesia is recognised as a high‐risk clinical intervention. These updated guidelines consider changes in prehospital practice and parallel changes in the practice of in‐hospital emergency anaesthesia, with the aim of encouraging standardised safe anaesthetic practice in a challenging clinical area.
David Lockey, Celestine Weegenaar, Imran Ahmad, Pascale Avery, Philip Cowburn, Richard M. Lyon, Giles Nordmann, Andrew J. Pountney, Cosmo F. M. Scurr, Matthew D. Wiles   +9 more
wiley   +1 more source

The "respiratory envelope", an aviation-inspired framework for patient tailored mechanical ventilation. [PDF]

Crit Care
Meuwese CL, Oppersma E, Somhorst P, Heunks L, Melkert JA, Jonkman AH.   +5 more
europepmc   +1 more source

Pre‐operative three‐dimensional face scans for predicting difficult facemask ventilation: a prospective development study

Anaesthesia, EarlyView.
Summary Introduction Facemask ventilation is a key airway management skill but predicting difficulty can be challenging. Pre‐operative three‐dimensional face scanning may have diagnostic value. We aimed to identify interpretable facial shape features and to quantify their value for predicting difficult facemask ventilation.
Viktor A. Wünsch, Hannes Bommes, Sofia Germer, Milan Piltan, Philipp Breitfeld, Sarah Latus, Linda Krause, Christian Zöllner, Christopher Gundler, Martin Petzoldt   +9 more
wiley   +1 more source

Effect of deep inspiration on impulse oscillometry responses to methacholine in healthy adults. [PDF]

Front Allergy
Ringbaek T, Folkmann T, Neumann S, Frølund L, Mortensen J, Ulrik CS, El Ali HH.   +6 more
europepmc   +1 more source

Prospective development and validation of an objective classification for difficult facemask ventilation: the MASCAN score

Anaesthesia, EarlyView.
Summary Introduction Difficult facemask ventilation is an entity that lacks a robust definition, leading to inconsistent identification in clinical practice and research. The aim of this study was to develop and validate an objective classification and numeric score for difficult facemask ventilation. Methods Four hundred patients who required tracheal
Viktor A. Wünsch, Hannes Bommes, Milan Piltan, Sofia Germer, Christopher Gundler, Thorsten Dohrmann, Vera Köhl, André Dankert, Linda Krause, Christian Zöllner, Philipp Breitfeld, Martin Petzoldt   +11 more
wiley   +1 more source

Take a deep breath: managing the challenges of acute respiratory distress syndrome cases. [PDF]

Trauma Surg Acute Care Open
Castillo-Angeles M, Salim A.
europepmc   +1 more source

In Vitro Performance of Valved Holding Chambers in Paediatric Asthma Controller Therapy

Acta Paediatrica, EarlyView.
ABSTRACT Aim Research on the drug delivery of inhaled corticosteroids and combination medications via valved holding chambers (VHCs) with children's breathing patterns is limited. We aimed to evaluate the in vitro performance of commercially available VHCs without facemasks under preschooler breathing conditions, focusing on total delivered dose and ...
Laura Ojanperä, Lauri Lehtimäki, Péter Csonka   +2 more
wiley   +1 more source