Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu +7 more
wiley +1 more source
Beyond Market Failure: A Critique of the ‘New Economics of Industrial Policy’
ABSTRACT In recent years, there has been an apparent tidal shift in neoclassical industrial policy scholarship as a ‘new economics of industrial policy’ has emerged. These scholars claim to have fundamentally repositioned the debate on industrial policy, supposedly offering a novel account of how, and why, states turn to industrial policy (the ‘new ...
Hamish William Ayton Evans
wiley +1 more source
THE RATIO OF NEURAL DRIVE TO TIDAL VOLUME MEASURED FROM SURFACE ELECTRODES CAN DETECT CLINICALLY SIGNIFICANT FALLS IN FEV1 IN ASTHMATIC SUBJECTS DURING HISTAMINE CHALLENGE [PDF]
openaire +1 more source
Abstract Housework is central to feminist calls for recognition of women's work, economic histories explaining the sexual division of labour, and claims regarding the progressive role of scientific knowledge. Yet little is known about the time it actually took. We address this lacuna.
Sara Horrell, Jane Humphries
wiley +1 more source
Balancing lung and brain: physiological strategies for ARDS management in acute brain injury. [PDF]
Robba C +12 more
europepmc +1 more source
Abstract Financial history is plagued by a visibility trap. Using the Brussels Stock Exchange (1850–1913), we demonstrate that asset illiquidity introduced selection bias, which systematically inflated historical risk premia. Applying a latent return model, we argue that correcting for this illiquidity decreases the equity and corporate bond risk ...
Justin Case +2 more
wiley +1 more source
Variation of perfusion index to evaluate fluid responsiveness during the preload challenge tests: a systematic review and meta-analysis. [PDF]
Huang H +5 more
europepmc +1 more source
Anaesthetic management of a horse with acute kidney injury
Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley +1 more source
Flow- versus Pressure-controlled Ventilation: Comment. [PDF]
Liu P.
europepmc +1 more source
Surgical management of congenital extrahepatic portosystemic shunt in a pony foal
Summary A five‐month‐old Welsh pony filly was admitted to the Veterinary Teaching Hospital of the University of Helsinki due to neurological signs. Clinicopathological findings showed elevated ammonium and bile acid levels. Computed tomography revealed an aberrant vessel originating from an enlarged splenic vein, leading to the right azygos vein ...
N. Hakonen +4 more
wiley +1 more source

