Results 81 to 90 of about 170,704 (305)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Benthic diel oxygen variability and stress as potential drivers for animal diversification in the Neoproterozoic-Palaeozoic

Nature Communications
The delay between the origin of animals in the Neoproterozoic and their Cambrian diversification remains perplexing. Animal diversification mirrors an expansion in marine shelf area under a greenhouse climate, though the extent to which these ...
Emma U. Hammarlund, Anuraag Bukkuri, Magnus D. Norling, Mazharul Islam, Nicole R. Posth, Etienne Baratchart, Christopher Carroll, Sarah R. Amend, Robert A. Gatenby, Kenneth J. Pienta, Joel S. Brown, Shanan E. Peters, Kasper Hancke   +12 more
doaj   +1 more source

Economic Impacts of Red Tide Events on Restaurant Sales [PDF]

The economic impact of red tide events were examined for three Southwest Florida waterfront restaurants. Daily gross sales from January 1996 through September were analyzed using a multiple regression time series model to examine whether the presence of ...
Morgan, Kimberly L., Larkin, Sherry L.
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The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source

Achieving High‐Instantaneous Pulse Power in Contact‐Separation TENG via Series Capacitive Voltage Control Architecture

Advanced Science, EarlyView.
Conventional contact‐separation triboelectric nanogenerators generate high voltage but deliver limited power due to premature charge dissipation. Here, a capacitive charge reservoir architecture decouples charge accumulation from discharge triggering, enabling sequential voltage amplification via floating‐layer capacitive coupling.
Ajay Haridas CP, Prosenjit Das, Kinsuk Naskar, Titash Mondal   +3 more
wiley   +1 more source

Nonlinear Interactions of Planetary‐Scale Waves in Mesospheric Winds Observed at 52°N Latitude and Two Longitudes

Geophysical Research Letters
Nine‐years of mesospheric wind measurements, from two meteor radars at 52°N latitude, were analyzed to study planetary waves (PWs) and tides through estimating their zonal wavenumbers.
Maosheng He, Jeffrey M. Forbes, Gunter Stober, Christoph Jacobi, Guozhu Li, Libo Liu, Jiyao Xu   +6 more
doaj   +1 more source

The Tides of Titan

Science, 2012
Getting to Know Titan Gravity-field measurements provide information on the interior structure of planets and their moons. Iess et al. (p. 457 ; published online 28 June) analyzed gravity data from six flybys of Saturn's moon, Titan, by the ...
L. Iess, R. A. Jacobson, M. Ducci, D. J. Stevenson, J. I. Lunine, J. W. Armstrong, S. W. Asmar, P. Racioppa, N. J. Rappaport, TORTORA, PAOLO   +9 more
openaire   +5 more sources

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Modeling Near-Surface Suspended Sediment Concentration in the English Channel

Journal of Marine Science and Engineering, 2015
The present study investigates the performances of the three-dimensional multicomponent hydro-sedimentary model ROMS (Regional Ocean Modeling System) to predict near-surface suspended sediment concentrations (SSC) in the English Channel (western Europe).
Nicolas Guillou, Aurélie Rivier, Francis Gohin, Georges Chapalain   +3 more
doaj   +1 more source

Rising Tide Center_Archive of Resources from WordPress [PDF]

, 2018
Archive of Rising Tide Center recources from ...
University of Maine Rising Tide Center
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