Results 211 to 220 of about 84,353 (275)

CRISPR tiling deletion screens reveal functional enhancers and allelic compensation effects (ACE) on SIN3A transcription. [PDF]

Nat Commun
Ren X, Zheng L, Liu Y, Maliskova L, Tam TW, Sun Y, Liu H, Cui X, Lee J, Takagi MA, Li B, Ren B, Wang W, Shen Y.   +13 more
europepmc   +1 more source

Assessing the role of urban blue space in summer outdoor thermal regulation in northwestern Europe: A hectometric Weather Research and Forecasting modelling on idealized urban landscape

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Using hectometric Weather Research and Forecasting simulations, we examine how urban blue spaces mitigate extreme summer heat in northwestern European cities through neighbourhood‐scale cooling mechanisms. Results show horizontal advection dominates cooling by mixing cooler air from waterbodies with warmer urban air, providing ∼50W·m−2$$ \sim 50\kern0 ...
Xuan Chen, Srinidhi Gadde, Arjan Droste, Gert‐Jan Steeneveld, Miriam Coenders‐Gerrits, Remko Uijlenhoet   +5 more
wiley   +1 more source

RNA structure modulates Cas13 activity and enables mismatch detection. [PDF]

Nat Biotechnol
Larsen BB, Kimchi O, Dunkley ORS, Grimm MS, Siegers JY, Huang Y, Vandavasi VG, Nguyen LT, Lamb CH, Aranovich I, Eggink D, Meijer A, Jalal H, Notterman DA, Karlsson EA, Te Velthuis AJW, Myhrvold C.   +16 more
europepmc   +1 more source

Simulating the year to minute wind spectrum with mesoscale‐coupled large‐eddy simulations

Quarterly Journal of the Royal Meteorological Society, EarlyView.
We coupled a large‐eddy simulation (resolution 50 m) to a mesoscale model (resolution 2 km), which takes boundary conditions from the ERA5 reanalysis. When using a large enough mesoscale domain (𝒪(1000 km)), the simulation setup can reproduce the observed temporal wind spectrum reasonably at all scales between one year and one minute. Furthermore, such
Bernard Postema, Chiel C. van Heerwaarden, Bart J.H. van Stratum, Pim van Dorp, Peter Baas, Harm J.J. Jonker   +5 more
wiley   +1 more source

GeneBits: ultra-sensitive tumour-informed ctDNA monitoring of treatment response and relapse in cancer patients. [PDF]

J Transl Med
Broche J, Kelemen O, Sekar A, Schütz L, Muyas F, Forschner A, Schroeder C, Ossowski S.   +7 more
europepmc   +1 more source

Parameter investigation for urban surface‐energy balance: A large‐eddy simulation study

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Large eddy simulation modelling is used to investigate the variation in surface‐energy balance (SEB) across an ensemble of morphometrically identical urban geometries. The geometries have the same plan‐area fraction, vegetated fraction, and frontal‐area index, but are unique in terms of building and green‐space layout.
Christopher E. Wilson, Jonathan K. P. Shonk, Sylvia I. Bohnenstengel, Athanasios Paschalis, Maarten van Reeuwijk   +4 more
wiley   +1 more source

Homotypic dendritic interactions constrain growth and receptor distribution in Drosophila T4 neurons without affecting orientation or function. [PDF]

Development
Özmen M, Drummond N, Haag J, Vieira RM, Pujol-Martí J, Borst A, Schilling T.   +6 more
europepmc   +1 more source

A new method to identify and explain sources of precipitation modification, illustrated for the western Netherlands

Quarterly Journal of the Royal Meteorological Society, EarlyView.
This study develops a method to identify the source areas of precipitation events, as illustrated for the western part of the Netherlands. Radar‐based precipitation data are traced back to their source areas and machine‐learning techniques are used to identify hypothesized causes: urban heat, surface roughness, and air pollution. We find that urban and
Jelmer van der Graaff, Gert‐Jan Steeneveld   +1 more
wiley   +1 more source

Aperiodicity in Low Dimensions. [PDF]

Materials (Basel)
Avramov PV, Tian H, Li L.
europepmc   +1 more source