Results 81 to 90 of about 19,962 (267)

Stage-specific transcriptomic responses of wheat to heat, drought, and combined stress: AP2/ERF regulatory networks and functional characterization of TaEREBP1-L

open access: yesBMC Plant Biology
Wheat (Triticum aestivum L.) production is increasingly constrained by drought, heat, and their combination, especially in arid regions like Xinjiang, China.
Junjie Han   +6 more
doaj   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan   +29 more
wiley   +1 more source

SiDT1 Defines Plant Architecture Reminiscent of Green Revolution in Foxtail Millet

open access: yesAdvanced Science, EarlyView.
SiDT1 encodes a GA3‐oxidase that creates a semi‐dwarf, lodging‐resistant architecture reminiscent of the rice Green Revolution. The resulting ideotype performs well under dense planting and provides a valuable genetic resource for high‐yield, mechanized foxtail millet production. ABSTRACT Foxtail millet (Setaria italica) is a drought‐tolerant C4 cereal
Jianzhen Lv   +13 more
wiley   +1 more source

Cation Diffusion‐Mediated Displaced Reaction‐Transformation in Green Steelmaking

open access: yesAdvanced Science, EarlyView.
The removal of O lattice atoms by environmental H2 at the surface of Fe3O4 results in Fe enrichment, driving the inward diffusion of Fe cations into the bulk. Through hopping between unoccupied and initially occupied sites, cation diffusion triggers a spatially displaced reaction‐transformation and drives subsequent dynamic phase transformations and ...
Guangyi Guo   +7 more
wiley   +1 more source

Isolation and Fast Selective Determination of Nor-abietanoid Diterpenoids from Roots Using LC-ESI-MS/MS with Multiple Reaction Monitoring

open access: yesNatural Product Communications, 2015
In the first part of this study we extracted, isolated, and identified the main diterpenoid constituents from the roots of a Central Asian medicinal and ornamental plant - Perovskia atriplicifolia Benth.
Sylwester Ślusarczyk   +5 more
doaj   +1 more source

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

open access: yesAdvanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma   +11 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

open access: yesAdvanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang   +13 more
wiley   +1 more source

Revolutionising Agricultural Sustainability: New ‘Furrow Tillage’ can Mitigate Short‐Term Soil‐to‐Atmosphere CO2 Flux and Promote Soil‐Plant‐Microbe Health

open access: yesAdvanced Science, EarlyView.
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar   +10 more
wiley   +1 more source

Detection and variable spraying of maize and weeds in residue covered fields via occlusion-aware modeling

open access: yesArtificial Intelligence in Agriculture
Straw mulching is an important practice in conservation tillage. Although it improves soil quality and moisture retention, it also creates strong occlusion between crops and weeds, which reduces the recognition accuracy of vision systems and limits the ...
Xinyue Zhang   +6 more
doaj   +1 more source

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