Results 51 to 60 of about 264,740 (325)

SAOLIM, a prototype of a low cost System for Adaptive Optics with Lucky Imaging

, 2010
A prototype of a low cost Adaptive Optics (AO) system has been developed at the Instituto de Astrofisica de Andalucia (CSIC) and tested at the 2.2m telescope of the Calar Alto observatory.
Aceituno, F. J., Aceituno, J., Ortiz, J. L., Sanchez, S. F.   +3 more
core   +1 more source

Variation in pelvic morphology may prevent the identification of anterior pelvic tilt [PDF]

, 2008
Pelvic tilt is often quantified using the angle between the horizontal and a line connecting the anterior superior iliac spine (ASIS) and the posterior superior iliac spine (PSIS).
Bowker, P, Graham-Smith, P, Herrington, LC, Nester, CJ, Preece, SJ, Willan, P   +5 more
core   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Hemodynamic Response to the Head-Up Tilt Test in Patients With Syncope as a Predictor of the Test Outcome: A Meta-Analysis Approach

Frontiers in Physiology, 2019
Aim: The paper presents a meta-analysis of studies comparing hemodynamic parameters: heart rate (HR), systolic blood pressure (sBP), diastolic blood pressure (dBP), and stroke volume (SV) measured during head-up tilt table test (HUTT) in patients with ...
Katarzyna Buszko, Sławomir Kujawski, Julia L. Newton, Paweł Zalewski   +3 more
doaj   +1 more source

Improved constraints on non-Newtonian forces at 10 microns

, 2008
Several recent theories suggest that light moduli or particles in "large" extra dimensions could mediate macroscopic forces exceeding gravitational strength at length scales below a millimeter.
Chiaverini, John, Geraci, Andrew A., Kapitulnik, Aharon, Smullin, Sylvia J., Weld, David M.   +4 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Study on Centroid Height Prediction of Non-Rigid Vehicle Based on Deep Learning Combined Model

Sensors
The height of the center of gravity (ZCG) is a critical parameter for evaluating vehicle safety and performance. Systematic errors arise in ZCG measurement via the tilt-table test method due to unlocked suspension systems and variable sprung mass ...
Guoqiang Pang, Zhiquan Xiao, Zhanwen Cai, Pei Wang   +3 more
doaj   +1 more source

Test of the isotropy of the speed of light using a continuously rotating optical resonator

, 2005
We report on a test of Lorentz invariance performed by comparing the resonance frequencies of one stationary optical resonator and one continuously rotating on a precision air bearing turntable.
A. A. Michelson, Achim Peters, Alexander Senger, B. R. Heckel, Evgeny Kovalchuk, Holger Müller, Sven Herrmann   +6 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

3D simulation of radiographic projections to test and reduce the effect of pelvic tilt on the accuracy of cross-table lateral radiography [PDF]

, 2020
Jie Xu, Baohua Su, Wenhui Zhang, Hao Sun, Deng Li, Zhiqing Cai, Meiyi Chen, Meiling Qiu, Ruofan Ma   +8 more
  +6 more sources