Results 231 to 240 of about 88,713,293 (287)

Commentary on differential impact of TIM-3 ligands on NK cell function. [PDF]

J Immunother Cancer
van de Ven R.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Single-cell sequencing analysis and machine learning model reveal aberrant TIM-3 expression in microglia during Alzheimer's disease progression. [PDF]

J Transl Med
Xu Z, Chen M, Liang F, Song S, Lei J, Huang X, Hu D, Tang L, Xu P, Lu L.   +9 more
europepmc   +1 more source

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis. [PDF]

Mol Med Rep
Yu M, Lu B, Liu Y, Me Y, Wang L, Li H.
europepmc   +1 more source

Immune checkpoint TIM-3 defines hyperactivated NK cells and predicts fatal outcome in severe fever with thrombocytopenia syndrome. [PDF]

PLoS Negl Trop Dis
Qian X, Zhang Y, Cheng Z, Song H, Huang L, Jia B, Li J, Wang J, Wu W.   +8 more
europepmc   +1 more source

The immune checkpoint TIM-3/HMGB-1 axis in myocardial infarction. [PDF]

NPJ Cardiovasc Health
Yousif LI, Sijtema AG, Appels Y, Screever EM, van Blokland IV, Oelen R, Groot HE, Gergely TG, Kocsis M, Leszek P, Varga ZV, Aboumsallem JP, der Harst PV, Franke LH, van der Wijst MGP, de Boer RA, Lipšic E, Meijers WC.   +17 more
europepmc   +1 more source

Modulating the tumor immune phenotypes by radiotherapy: formulating and validating the combination therapy of radiation, PD-L1, and TIM-3 blockade in colorectal cancer. [PDF]

J Immunother Cancer
Wang XX, Zhu C, Sun Y, Xie X, Wang M, Jin Y, Gu Y, Qian L, Shi L, Xu J, Wang F, Huang X, Dai S, Sun X.   +13 more
europepmc   +1 more source

TIM-3 expression in tumor and stromal cells are associated with the prognosis in patients with epithelial ovarian cancer. [PDF]

Medicine (Baltimore)
Wu J, Zhang Y, Zhang H, Li Y, Jie Z, Kang S.   +5 more
europepmc   +1 more source

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TIM-3: An Update on Immunotherapy

International Immunopharmacology, 2021
T cell immunoglobulin and mucin domain 3 (TIM-3) was originally found to be expressed on the surface of Th1 cells, acting as a negative regulator and binding to the ligand galectin-9 to mediate Th1 cell the apoptosis. Recent studies have shown that TIM-3 is also expressed on other immune cells, such as macrophages, dendritic cells, and monocytes.
Lizhen Zhao, Lin Fan
exaly   +3 more sources