Results 121 to 130 of about 29,851,130 (293)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Controller Design of Multiinput Multioutput Time-Delay Large-Scale System

open access: yesAbstract and Applied Analysis, 2013
The paper presents a novel feedback linearization controller of nonlinear multiinput multioutput time-delay large-scale systems to obtain both the tracking and almost disturbance decoupling (ADD) performances.
Chia-Wei Lin   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Research on the Simulation of Time-Delay System

open access: yesComputer and Information Science, 2011
Most of modern industrial processes is continuous, large-scale and complex. Large time-delay system is increasingly common in the process of industrial production. It is difficult to make the system satisfy the performance specification requirements by traditional Proportional-Integral-Derivative (PID) control.
openaire   +2 more sources

Positional Modeling in a System with Time Delay [PDF]

open access: yes, 2003
The problem of dynamical modeling of unknown control of a system described by equations with time delay is discussed. The constructed algorithm operate synchronically with a process under consideration. It is stable with respect to informational noises and computational errors.
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Time Parameter Optimization for the Semiconductor Laser-Based Time-Delay Reservoir Computing System

open access: yesPhotonics
Time-delay reservoir computing (RC) systems, particularly those based on semiconductor lasers (SLs), have gained attention due to their low energy consumption, high response rates, and rich nonlinear dynamics.
Qiudi Li   +5 more
doaj   +1 more source

Analysis of delay fluctuationsin two-way time transfer earth stations

open access: yes, 2012
[[abstract]]The delay fluctuations in earth stations have become the main source of instability that degrades the accuracy of two-way satellite time and frequency transfer.
W. H. Tseng;H. T. Lin;P. C. Chang;S. Y. Lin;K. M. Feng
core  

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