Results 121 to 130 of about 2,427,094 (264)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Heart Rate Variability Time-Domain Analysis Across Glaucoma Subtypes. [PDF]

Biomedicines
Yoshida Y, Takei H, Ukisu M, Takagi K, Tanito M.   +4 more
europepmc   +1 more source

Finite-difference time-domain analysis of increased penetration depth in optical coherence tomography by wavefront shaping. [PDF]

Biomed Opt Express, 2018
Kim JU, Choi H, Park Y, Shin J.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Heart rate variability reveals graded task difficulty effects and sensitization dynamics in anticipatory psychological stress via time-domain analysis. [PDF]

J Physiol Anthropol
Jian Z, Huang J, Shi F, Shimomura Y.
europepmc   +1 more source

On Time Domain Analysis of Photoplethysmogram Signals for Monitoring Heat Stress. [PDF]

Sensors (Basel), 2015
Elgendi M, Fletcher R, Norton I, Brearley M, Abbott D, Lovell NH, Schuurmans D.   +6 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Time-Domain Analysis of Chest Impedance for Venous Air Embolism Detection: An Open-Source Software Tool and Single-Cadaver Pilot Study. [PDF]

Cureus
Marcellino C, Johnston M, Robinson N, Abcejo AS.   +3 more
europepmc   +1 more source

Time-domain analysis of scrotal thermoregulatory impairment in varicocele. [PDF]

Front Physiol, 2014
Ismail E, Orlando G, Pompa P, Gabrielli D, Di Donato L, Cardone D, Merla A.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source