Results 101 to 110 of about 33,733,084 (204)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Hybrid frequency–time domain models for dynamic response analysis of marine structures

open access: yes, 2008
Time-domain models of marine structures based on frequency domain data are usually built upon the Cummins equation. This type of model is a vector integro-differential equation which involves convolution terms.
Taghipour, Reza   +2 more
core   +1 more source

Discharge propagation analysis of regional and basin floods in the middle and lower reaches of the Yangtze River

open access: yesShui kexue jinzhan
Flood propagation is pivotal to flood control security,affecting channel erosion-deposition processes,fluvial regime evolution,and river-lake interactions. Analyzing the composition and downstream variability of typical floods in the frequency domain has
Hongyang ZHANG   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Analysis on Wind-Induced Fatigue Life of Steel Tall Buildings Based on Wind Tunnel Test and Time-Domain Analysis

open access: yesApplied Sciences
Dynamic wind-induced vibrations of structures will cause cyclic stresses in structural elements, potentially leading to fatigue damage accumulation or structural failure.
Ze-Kang Wang, Rui-Fang Gao, Lei Wang
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Noise Propagation and Mitigation in High-Rise Buildings Under Urban Traffic Impact

open access: yesBuildings
Urban traffic noise poses escalating environmental challenges in rapidly urbanizing regions with high-density buildings, yet systematic investigations into its spatiotemporal characteristics remain relatively scarce.
Shifeng Wu   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Enhanced DC Series Arc-Fault Detection in LVDC Systems With Capacitor-Assisted Impedance Shaping

open access: yesIEEE Access
A DC grid can achieve high power conversion efficiency by reducing conversion stages between DC energy resources and loads. However, as system complexity increases, DC distribution systems face series arc faults due to damaged power cables and loose ...
Chun-Sung Kim   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy