Results 81 to 90 of about 4,622,355 (269)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Analysis of offshore wind turbine operation & maintenance using a novel time domain meteo-ocean modeling approach [PDF]

, 2012
This paper presents a novel approach to repair modeling using a time domain Auto-Regressive model to represent meteo-ocean site conditions. The short term hourly correlations, medium term access windows of periods up to days and the annual distibution of
Dinwoodie, Iain Allan, McMillan, David, Quail, Francis   +2 more
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Brillouin optical time-domain analysis for geotechnical monitoring

Journal of Rock Mechanics and Geotechnical Engineering, 2015
In this paper, we show some recent experimental applications of Brillouin optical time-domain analysis (BOTDA) based sensors for geotechnical monitoring.
L. Zeni, L. Picarelli, B. Avolio, A. Coscetta, R. Papa, G. Zeni, C. Di Maio, R. Vassallo, A. Minardo   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Real Wages and the Business Cycle in Germany [PDF]

This paper establishes stylized facts about the cyclicality of real consumer wages and real producer wages in Germany. As detrending methods we apply the deterministic trend model, the Beveridge-Nelson decomposition, the Hodrick-Prescott filter, the ...
Beissinger, Thomas, Marczak, Martyna
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Analysis on Wind-Induced Fatigue Life of Steel Tall Buildings Based on Wind Tunnel Test and Time-Domain Analysis

Applied Sciences
Dynamic wind-induced vibrations of structures will cause cyclic stresses in structural elements, potentially leading to fatigue damage accumulation or structural failure.
Ze-Kang Wang, Rui-Fang Gao, Lei Wang
doaj   +1 more source

Analysis of Cavitation-induced Vibration Characteristics of a Vortex Pump Based on Adaptive Optimal Kernel Time-frequency Representation [PDF]

Journal of Applied Fluid Mechanics
Cavitation-induced vibration presents a significant challenge in vortex pumps, leading to potential damage to hydraulic components and adverse effects on pump performance. This study aims to investigate the long-term implications of such phenomena.
Y. Wang, P. Zhou, C. Zhou, W. Zhou, J. Li   +4 more
doaj   +1 more source