Results 181 to 190 of about 42,446 (256)

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

Amorphous-to-crystalline transformation: a mechanochemical pathway to imine-linked covalent organic frameworks. [PDF]

RSC Mechanochem
Brown N, Nailwal Y, Blair T, Alsudairy Z, Zhang Q, Kennedy K, Liu Y, Li X.   +7 more
europepmc   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

The FEBS Journal, EarlyView.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil, Haocheng Qianzhu, Elwy H. Abdelkader, Adarshi P. Welegedara, Josemon George, Christoph Nitsche, Thomas Huber, Gottfried Otting   +7 more
wiley   +1 more source

Peptide-Functionalized Gold Nanorods as a Model to Reach the Cell Nucleus: Synthesis and Structural Characterizations in View of Theragnostic Applications. [PDF]

J Phys Chem B
Binelli L, Bertelà F, Amatori S, Lipani D, Battocchio C, Iucci G, Tortora L, Dini V, Grande S, Palma A, Ranaldi M, De Berardis B, Ammendolia MG, Mancini-Terraciano C, Fabbri A, Attili A, Scotognella T, Giordano A, Calcagni ML, Dettin M, Zamuner A, Maraloiu VA, Venditti I.   +22 more
europepmc   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Electrocatalytic Hydrogen Evolution Using Cyano-Substituted Triaryl Corrole Antimony(III) Complexes. [PDF]

Molecules
Wang YY, Wu TL, Guo DY, Zhang H, Sun YM, Si LP, Liu HY.   +6 more
europepmc   +1 more source

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

The FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer, Guiseppa de Rocco, Moritz Völker‐Albert, Ignasi Forne, Nicoletta Landsberger, Axel Imhof, Shibojyoti Lahiri   +6 more
wiley   +1 more source

Fe₃O₄@SiO₂-NH₂-ECH-HMTA-Supported Trifluoroacetic Acid: A Magnetically Recyclable Catalyst for One-Pot Synthesis of Imidazole-Indole Derivatives. [PDF]

ACS Omega
Tongkhan S, Mokkarat A, Radchatawedchakoon W, Kruanetr S, Pilasombat R, Sakee U.   +5 more
europepmc   +1 more source

Evaluating Nurses' Perspectives on the Acceptability and Practicality of Comfort Rounding for Personalised Nutritional and Mobility Care in Surgical Wards: A Mixed‐Methods Feasibility Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To evaluate nurses' perspectives on factors influencing the acceptability and practicality of comfort rounding, focussing on personalised nutritional and mobility care. Design Mixed‐methods feasibility study. Methods Focus group interviews with nurses were conducted before, during and at the end of the implementation period (2022–2023).
Femke Becking‐Verhaar, Fanny Pelzer, Harm Van Noort, Cariline Roosen, Yvonne Van Eijk‐Hustings, Marian De Van Der Schueren, Hester Vermeulen, Getty Huisman‐De Waal   +7 more
wiley   +1 more source

Integrated Targeted and Suspect Screening Workflow for Identifying PFAS of Concern in Urban-Impacted Serbian Rivers. [PDF]

Toxics
Antić I, Buljovčić M, Cochran RE, Živančev J, Llorca M, Farré M, Rakić D, Tautenhahn R, Đurišić-Mladenović N.   +8 more
europepmc   +1 more source