Results 141 to 150 of about 124,888,785 (314)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A study of some M[x]/G/1 type queues with random breakdowns and bernouilli schedule server vacations based on a single vacation policy

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Queueing systems arise in modelling of many practical applications related to computer sciences, telecommunication networks, manufacturing and production ...
Maraghi, Farzana Abdulla
core  

Deep Learning Approaches for Robust Time of Arrival Estimation in Acoustic Emission Monitoring. [PDF]

open access: yesSensors (Basel), 2022
Zonzini F   +5 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Estimação de tempos de chegada de ônibus urbano utilizando filtros de Kalman [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Automação e Sistemas.A fim de diminuir congestionamentos, poluição do ar, consumo de combustível, entre outros, tem-se buscado
Gurgel, Felipe Sanches
core  

Fusion of time of arrival and time difference of arrival for ultra-wideband indoor localization

open access: yes, 2022
S.1-8This article presents a time of arrival and time difference of arrival fusion for Decawave ultra-wideband transceivers. The presented techniques combine the time-of-arrival and time-difference-of-arrival measurements without losing the advantages of
Arens, Michael   +4 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Adjoint-state differential arrival time tomography

open access: yes
The recently developed adjoint-state traveltime tomography (ATT) method offers an alternative approach to conduct traveltime tomography without the need for ray tracing or waveform modelling.
Li, Tianjue   +3 more
core   +1 more source

Determination of P – wave arrival time of acoustic events [PDF]

open access: yesActa Montanistica Slovaca, 2010
The new approach to the P-wave arrival time determination based on acoustic emission data from loading experiments is tested.The algorithm used in this paper is built on the STA/LTA function computed by a convolution that speeds up the computation ...
Matěj Petružálek   +2 more
doaj  

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