Results 151 to 160 of about 314,397 (335)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Optimization of midcourse velocity corrections [PDF]

open access: yes
Optimum time to apply single midcourse velocity correction and optimum schedule for corrections in variable time-of-arrival guidance - geometrical ...
Potter, J. E., Stern, R. G.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

What Bohmian mechanic says about arrival times of 1D vacuum squeezed states

open access: yesJournal of Physics Communications
We calculate the time of arrival probability distribution of a quantum particle using the Bohmian formalism. The pilot-wave is given by the wave function of the one dimensional vacuum squeezed state written in the Schrödinger representation.
Angel Garcia-Chung, Humberto G Laguna
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Indoor positioning in 5G new radio: how it works, status quo of research, and the road ahead

open access: yesICT Express
In this paper, the architecture and mechanism of 5G New Radio indoor positioning schemes such as downlink time difference of arrival (DL-TDOA), uplink (UL) TDOA, multiple-cell round trip time (Multi-RTT), DL angle of departure, UL angle of arrival (AOA),
Jiaqi Li, Seung-Hoon Hwang
doaj   +1 more source

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