Results 171 to 180 of about 124,888,785 (314)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Valuation of uncertainty in travel time and arrival time - some findings from a choice experiment [PDF]
We are developing a dynamic modeling framework in which we can evaluate the effects of different road pricing measures on individual choice behavior as well as on a network level.
Michiel Bliemer, Dirk Van Amelsfort
core
Time and Quantum Theory: A History and A Prospectus [PDF]
, 2013 In this paper I am concerned with analyzing in detail how ideas and expectations regarding the role of time in quantum theory arose and evolved in the early years of quantum mechanics (from 1925-27).
Tom Pashby, Pashby, Thomas
core
Traffic congestion prediction based on Estimated Time of Arrival. [PDF]
PLoS One, 2020 Zafar N, Ul Haq I.
europepmc +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
An appraisal of QR code use to deliver bus arrival time information at bus stops in Southampton
, 2011 The provision of at-stop bus arrival time information has numerous potential benefits to bus users. With real-time passenger information well established in the UK the challenge is relaying accurate bus arrival times to passengers in a cost effective ...
Gammer, Nick
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Time-of-arrival detection for time-resolved scanning transmission X-ray microscopy imaging. [PDF]
J Synchrotron Radiat, 2020 Finizio S, Mayr S, Raabe J.
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source