Results 201 to 210 of about 271,810 (264)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Estimation of spatiotemporal poisson processes with missing data. [PDF]

Sci Rep
Guigues V, Kleywegt A, Nascimento VH, de Andrade LR.   +3 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Avoidance of simultaneous patch use in Japanese large-footed bats. [PDF]

PLoS One
Fujioka E, Shiraishi M, Hirao T, Onishi Y, Fukui D, Hiryu S.   +5 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Optimization of Sensor Network for Velocity-Free Acoustic Emission Source Localization in Construction Materials. [PDF]

Materials (Basel)
Huang X, Liu Y, Yang L, Dong L.
europepmc   +1 more source

Association between total prehospital time and early mortality in patients with severe torso trauma: a retrospective study at an urban Emergency and Critical Care Center. [PDF]

Int J Emerg Med
Iwasaki M, Kojima M, Mochida Y, Nakamoto R, Shoko T.   +4 more
europepmc   +1 more source

Breeding phenology plasticity to climate revealed by automated monitoring of two Eudpytes penguin species across the sub-Antarctic. [PDF]

Sci Rep
Dodino S, Juárez Martínez I, Edney AJ, Pütz K, Barrionuevo M, Frere E, Millones A, Morgenthaler A, Quillfeldt P, Reusch K, Raya Rey A, Hart T.   +11 more
europepmc   +1 more source