Results 51 to 60 of about 166,462,105 (278)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

High-Precision Time Difference of Arrival Estimation Method Based on Phase Measurement

Remote Sensing
In unmanned aerial vehicle (UAV)-based time difference of arrival (TDOA) positioning technique, baselines are limited due to communication constraints. In this case, the accuracy is highly sensitive to the TDOA measurements’ error. This article primarily
Jihao Xin, Xuyang Ge, Yuan Zhang, Xingdong Liang, Hang Li, Linghao Wu, Jiashuo Wei, Xiangxi Bu   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Research of Batch Scheduling with Arrival Time Based on Estimation of Distribution Algorithm

, 2014
Estimation of distribution has been used to solve the batch scheduling problem with job release problem, which minimizing the make span as the objective function.
Xiaofeng Zhou, Chang Liu, Li D(李冬), Peng FF(彭菲菲), Dong Li, Feifei Peng, Zhou XF(周晓锋), Liu C(刘昶)   +7 more
core   +1 more source

Noise resistant method for cardiac pulse wave arrival time estimation / [PDF]

, 2014
Pulse arrival time is the time interval which is needed for pulse wave to travel the distance from the heart to some distal place on the body. Almost all definitions of pulse arrival time estimation are based on high quality photoplethysmogram signals ...
Rapalis, A.,, Marozas, V., Rapalis, A., Lukosevicius, A., Janusauskas, A.,, Lukosevicius, A.,, Marozas, V.,, Janusauskas, A.   +7 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Two-Dimensional Underdetermined DOA Estimation of Quasi-Stationary Signals using Parallel Nested Array [PDF]

Radioengineering, 2020
In this paper, a two dimensional underdetermined direction of arrival estimation (DOA) of quasi-stationary signals using a parallel nested array structure is investigated.
X. Y. Pan, Q. P. Xie, J. Y. Chen, S. P. Xiao   +3 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source