Results 61 to 70 of about 166,462,105 (278)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Deep Learning-Based Travel Time Estimation in Hiking with Consideration of Individual Walking Ability

Cybernetics and Information Technologies
Hiking is popular, but mountain accidents are serious problems. Accurately predicting hiking travel time is an essential factor in preventing mountain accidents.
Asako Mizuho, Tahara Yasuyuki, Ohsuga Akihiko, Sei Yuichi   +3 more
doaj   +1 more source

Robust Blind Algorithm for DOA Estimation Using TDOA Consensus

Acoustics
This paper proposes a robust blind algorithm for direction of arrival (DOA) estimation in challenging acoustic environments. The method introduces a novel Time Difference of Arrival (TDOA) consensus framework that effectively identifies and filters ...
Danilo Greco
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Approximate maximum likelihood estimation of two closely spaced sources [PDF]

, 2014
The performance of the majority of high resolution algorithms designed for either spectral analysis or Direction-of-Arrival (DoA) estimation drastically degrade when the amplitude sources are highly correlated or when the number of available snapshots is
Chaumette, Eric, Besson, Olivier, Vincent, François   +2 more
core   +1 more source

An Error Analysis Method for Correlation-Based Parameter Estimators in Discrete-Time Signals Under Gaussian Noise

IEEE Access
In this study, we expand on a previously introduced method for computing the error statistics associated with estimating the time of arrival of a known signal in sampled data with additive white Gaussian noise (AWGN).
Chris Hall, Ivan Djordjevic
doaj   +1 more source

A Novel Method for DOA and Time Delay Joint Estimation in Multipath OFDM Environment

International Journal of Antennas and Propagation, 2020
Joint time delay and direction of arrival estimation based on uniform linear arrays in Orthogonal Frequency Division Multiplexing (OFDM) systems has to face the problems posed by coherent multipath environments and high computational complexity.
Xiangzhi Li, Weijia Cui, Haiyun Xu, Bin Ba, Yankui Zhang   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source