Results 61 to 70 of about 1,114,747 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Integrating Twitter Traffic Information with Kalman Filter Models for Public Transportation Vehicle Arrival Time Prediction

, 2015
Accurate bus arrival time prediction is key for improving the attractiveness of public transport, as it helps users better manage their travel schedule.
Hussain, Amir, Amir Hussain, Abidin, Ahmad Faisal, Ahmad Faisal Abidin, Mario Kolberg, Kolberg, Mario   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Probability hypothesis density filtering for real-time traffic state estimation and prediction [PDF]

, 2013
The probability hypothesis density (PHD) methodology is widely used by the research community for the purposes of multiple object tracking. This problem consists in the recursive state estimation of several targets by using the information coming from an
El Faouzi, Nour Eddin, Mihaylova, Lyudmila, Canaud, M., Faouzi, Nour-Eddin El, Sau, Jacques, Canaud, Matthieu, El Faouzi, Nour-Eddin, Mihaylova, L., Sau, J., El Faouzi, N.E.   +9 more
core   +1 more source

Two-Dimensional Underdetermined DOA Estimation of Quasi-Stationary Signals using Parallel Nested Array [PDF]

Radioengineering, 2020
In this paper, a two dimensional underdetermined direction of arrival estimation (DOA) of quasi-stationary signals using a parallel nested array structure is investigated.
X. Y. Pan, Q. P. Xie, J. Y. Chen, S. P. Xiao   +3 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A New Adaptive Constrained LMS Time Delay Estimation Algorithm

, 2011
In this paper, a new adaptive constrained LMS time delay estimation (TDE) algorithm is devised. It is known that in the TDE problem, the time differences between relevant sensors can be modeled as a finite impulse response (FIR) filter whose weight ...
陳巽璋; Lin, S.N.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Investigation and development of DSP algorithms/hardware for real time power spectral density estimation [PDF]

, 1993
This research is concerned with the Power Spectrum Density Estimation with em- phasIze on the bigh-resolution algorithms and their real-time implementations. Tl-ie classical PSD estimation methods are fast and robust.
Sung-Yuan, Ko
core