Results 51 to 60 of about 16,304,775 (272)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Isolated and combined effects of high-intensity interval training and time-restricted eating on glycaemic control in reproductive-aged women with overweight or obesity: study protocol for a four-armed randomised controlled trial

BMJ Open, 2021
Introduction Overweight and obesity in reproductive-aged women is a global problem due to the increased risk of subfertility, pregnancy complications and cardiometabolic diseases.
Trine Moholdt, Stian Lydersen, Catalina P Silva, John A Hawley   +3 more
doaj   +1 more source

Time-Restricted Eating: A Novel Dietary Strategy for Cardiac Rehabilitation

Canadian Journal of Cardiology, 2023
Cardiac rehabilitation (CR) is a multimodal program considered to be the standard of care for secondary prevention of cardiovascular disease (CVD). The primary goals of CR are managing CVD risk factors and improving quality of life. Exercise is the cornerstone, but nutrition education delivered by registered dietitians (RDs) is a core component of CR ...
Stephanie Small, Josep Iglesies-Grau, Chantal Gariepy, Michael Wilkinson, Pam Taub, Amy Kirkham   +5 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Negative mood induction effects on problem-solving task in women with eating disorders: a multi-method examination [PDF]

, 2022
BACKGROUND: The effects of negative affect on problem-solving and its psychophysiological correlates are poorly understood in eating disorder populations.
French, Elan N., Arlt, Jean M., Chen, Eunice Y., Yiu, Angelina, Eneva, Kalina, Chen, Eunice, Chen|   +6 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized con of trial

, 2023
Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized con of ...
Michael Wheeler (13086588), Joan M Senden (14323485), Joy PB Goessens (14323488), Imre WK Kouw (14323476), Bridget E Radford (14323479), Rebecca C Hall (14323482), Evelyn B Parr (12909761), Luc JC van Loon (11220244), John A Hawley (12909764)   +8 more
core  

Intermittent fasting and neurocognitive disorders: What the evidence shows

The Journal of Nutrition, Health and Aging
Introduction: Intermittent fasting (IF) has emerged as a potential lifestyle intervention for mitigating cognitive decline and enhancing brain health in individuals with mild to major neurocognitive disorders.
Jordan Beveridge, Allison Montgomery, George Grossberg   +2 more
doaj   +1 more source

Time-restricted eating (16/8) and energy-restricted diet: effects on diet quality, body composition and biochemical parameters in healthy overweight females

BMC Nutrition, 2023
Background Time-restricted eating (TRE) is a current popular dietary strategy for noncommunicable diseases. However, studies demonstrated contradictory results for it and in all dietary strategies, diet quality is an the important part of the well-being.
Özge Mengi Çelik, Eda Köksal, Müjde Aktürk   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source