Results 91 to 100 of about 305,083 (282)

5G Physical Layer-Based Procedure to Support Time-Sensitive Networking

open access: yesTelecom
Deploying 5G in new and diverse use cases, such as Industry 4.0 and factory automation, requires 5G systems to harmonize with the communication technologies used in these industries.
Faiza Bouchmal   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Time-Sensitive Networking Digital Twin for STRIDE-based security testing

open access: yesEURASIP Journal on Information Security
Time-sensitive networking is set to play a pivotal role in the evolution of modern industrial and 5G networks, enabling them to meet the strictest communication requirements for guaranteed low latency and high reliability.
Andrea Melis   +2 more
doaj   +1 more source

Proposal and Investigation of a Lite Time Sensitive Networking Solution for the Support of Real Time Services in Space Launcher Networks

open access: yesIEEE Access
Most launcher networks are based on proprietary buses such as MIL-STD-1553B whose low bandwidth limits the introduction of new services of suitable characteristics. Ethernet technology, because of its low cost and high performance, has been considered an
Tiziana Fiori   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

TALESS: TSN With Legacy End-Stations Synchronization

open access: yesIEEE Open Journal of the Industrial Electronics Society
In order to facilitate the adoption of Time Sensitive Networking (TSN) by the industry, it is necessary to develop tools to integrate legacy systems with TSN.
Daniel Bujosa Mateu   +4 more
doaj   +1 more source

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