Results 81 to 90 of about 305,083 (282)
All or nothing: this is the question? The application of article 3(2) Data Protection Directive 95/46/EC to the Internet [PDF]
, 2008 The Data Protection Directive 95/46/EC (hereinafter the “Directive”) was passed in 1995 to harmonise the national data protection laws within the European Community with the aim of protecting the fundamental rights and freedoms of individuals including ...
Savirimuthu, J, Wong, R
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Social media: Do context limitations exist? [PDF]
, 2012 Since the inception of popular social networking sites, such as MySpace, Facebook and Twitter, millions of people around the world are becoming members of their own virtual communities that continue to grow.
Fortier, Richard
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Collaboration and the Net generation: The changing characteristics of first year university students [PDF]
, 2009 This paper reports on the first phase of research that investigates the Net generation entering university. The paper focuses on claims about the Net generation’s relationship to collaboration and cooperation and the ways that this relationship is ...
Jones, Chris, Ramanau, Ruslan
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Software-defined time-sensitive networking for hybrid multi-domain networking
Tongxin xuebaoTo address the problem of deterministic end-to-end transmission in hybrid multi-domain networks, a software-defined time-sensitive network organization solution was proposed.
GUO Mengjie +3 more
doaj
Young people's views regarding participation in mental health and wellbeing research through social media [PDF]
, 2015 Social media is a central component in the lives of many young people, and provides innovative potential to conduct research among this population. Ethical issues around online research have been subject to much debate, yet young people have seldom ...
Cardoso, Patricia +5 more
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source