Results 61 to 70 of about 424,943 (312)

GLOBE: A novel pruning-based sparse modeling with application to time series data representation

Journal of King Saud University: Computer and Information Sciences, 2023
In the past years, Sparse Modeling (SM) has been used in a variety of applications, such as data representation. In this type of data modeling, the data is divided into small segments, and each one is processed independently using SM techniques to find ...
A.N. Omara, Abdullah Shawan Alotaibi
doaj   +1 more source

Time Series Representation Models

Time series analysis remains a major challenge due to its sparse characteristics, high dimensionality, and inconsistent data quality. Recent advancements in transformer-based techniques have enhanced capabilities in forecasting and imputation; however, these methods are still resource-heavy, lack adaptability, and face difficulties in integrating both ...
Leppich, Robert, Borst, Vanessa, Lesch, Veronika, Kounev, Samuel   +3 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Dynamic Sub-Sequence Warping: A Representation-Based Similarity Measure for Long Time Series

Data Science and Engineering
Dynamic time warping (DTW), a typical elastic similarity measure that compares one-to-many points, has been proven effective for various time-series data mining tasks. However, it requires a quadratic time complexity $$O(n^2)$$ proportional to the length
Zhou Zhou, Gang Huang, Laura Dawkins
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Time-Series Representation and Clustering Approaches for Sharing Bike Usage Mining

IEEE Access, 2019
Massive bike-sharing systems (BSS) usage and performance data have been collected for years over various locations. Nevertheless, researchers encountered several challenges while dealing with massive BSS data. The challenges that could be enhanced in the
Duo Li, Yifei Zhao, Yan Li
doaj   +1 more source

CARLA: Self-supervised Contrastive Representation Learning for Time Series Anomaly Detection [PDF]

, 2023
Zahra Zamanzadeh Darban, Geoffrey I. Webb, Shirui Pan, Charų C. Aggarwal, Mahsa Salehi   +4 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A Multirepresentational Fusion of Time Series for Pixelwise Classification

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
This article addresses the pixelwise classification problem based on temporal profiles, which are encoded in 2-D representations based on recurrence plots, Gramian angular/ difference fields, and Markov transition field.
Danielle Dias, Allan Pinto, Ulisses Dias, Rubens Lamparelli, Guerric Le Maire, Ricardo da S. Torres   +5 more
doaj   +1 more source