Results 121 to 130 of about 15,525,035 (313)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Stability Analysis of Linear Time-Varying Delay Systems via a Novel Augmented Variable Approach

open access: yesMathematics
This paper investigates the stability issues of time-varying delay systems. Firstly, a novel augmented Lyapunov functional is constructed for a class of bounded time-varying delays by introducing new double integral terms.
Wenqi Liao, Hongbing Zeng, Huichao Lin
doaj   +1 more source

A Novel Approach to Delay-Variation-Dependent Stability Analysis of 2-D Discrete-Time Systems With Mixed Delays

open access: yesIEEE Access, 2019
In this paper, a stability analysis problem is studied for a class of two-dimensional (2-D) discrete-time systems with time-varying and distributed delays described by the second Fornasini-Marchesini (FM) model. First, new 2-D polynomials-based summation
Dan Peng, Hongshuang Xu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Stability of cellular neural networks with unbounded time-varying delays

open access: yesElectronic Journal of Differential Equations, 2008
In this article, we prove the existence of local solutions and the stability of the equilibrium points for cellular neural networks.
Jianying Shao, Lijuan Wang
doaj  

Reduction model approach for systems with a time-varying delay

open access: yes2015 54th IEEE Conference on Decision and Control (CDC), 2015
We provide a reduction model approach for achieving global exponential stabilization of linear systems with a time-varying pointwise delay in the input. We allow the delay to be discontinuous and uncertain. We also provide a stability result based on a different dynamic extension that ensures input-to-state stability with respect to additive ...
Mazenc, Frederic, Malisoff, Michael
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

On the modeling of time-varying delays [PDF]

open access: yes, 2004
This thesis is an effort to develop generalized dynamic models for systems with time-varying time delays. Unlike the simple time-delay model characterized by a transportation lag in the case of a fixed time delay, time-varying delays exhibit quite ...
Shah, Chirag Laxmikant
core   +3 more sources

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