Results 101 to 110 of about 15,525,035 (313)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Global projective lag synchronization of fractional order memristor based BAM neural networks with mixed time varying delays [PDF]

, 2019
This paper addresses Master-Slave synchronization for some memristor- based fractional-order BAM neural networks (MFBNNs) with mixed time varying delays and switching jumps mismatch.
Cao, J., Grienggrai Rajchakit, Anbalagan Pratap, Pratap, A., Jinde Cao, Bagdasar, O., Ovidiu Bagdasar, Ramachandran Raja, Rajchakit, G., Chandran Sowmiya, Raja, R., Sowmiya, C.   +11 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Robust H∞ filtering for networked systems with multiple state delays [PDF]

, 2007
This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Taylor & Francis Ltd.In this paper, a new robust H∞ filter design problem is studied for a class of networked systems with ...
XIAO He, He, X, Wang, Z, Zhou, D, ZIDONG Wang, D. Zhou   +5 more
core   +1 more source

Estimating time-varying treatment effects in longitudinal studies

, 2023
Longitudinal study designs are frequently used to investigate the effects of a naturally observed predictor (treatment) on an outcome over time. Because the treatment at each time point or wave is not randomly assigned, valid inferences of its causal ...
Dongning Ren, Wen Wei Loh
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

H ? filtering for stochastic singular fuzzy systems with time-varying delay [PDF]

, 2014
This paper considers the H? filtering problem for stochastic singular fuzzy systems with timevarying delay. We assume that the state and measurement are corrupted by stochastic uncertain exogenous disturbance and that the system dynamic is modeled ...
Cai, Min, Yan, Xinggang, Zhao, Feng, Zhang, Qingling   +3 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Exponential stability of uncertain systems with time-varying delays

, 2004
This paper investigates the exponential stability of a class of uncertain systems with multiple time-varying delays with a new approach. Time delays are assumed to be bounded, independent and arbitrary-varying with only each bound known.
Jing XJ(景兴建), Wang YC(王越超)
core  

Robust H∞ control for a class of nonlinear stochastic systems with mixed time delay [PDF]

, 2007
This is the post print version of the article. The official published version can be obtained from the link - Copyright 2007 Wiley-Blackwell LtdThis paper is concerned with the problem of robust H∞ control for a class of uncertain nonlinear Itô-type ...
Liu, Y, Zidong Wang, Liu, X, Wang, Z, Yurong Liu, Xiaohui Liu   +5 more
core   +1 more source