Results 81 to 90 of about 16,837,259 (303)

Linear Time-Varying Logistic Model With Shape Parameter for Dynamic Epidemic Modeling

Journal of Applied Mathematics
We propose extending the logistic growth model by introducing a Linear Time-Varying Logistic Model with Shape Parameter (LTVLMS). This model incorporates a time-varying linear growth rate function, rt=r0+r1t, along with a shape parameter ν to allow for ...
Redouane Betrouni, Tewfik Kernane
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Estimating Time-Varying Policy Neutral Rate in Real Time [PDF]

This paper examines policy neutral rate in real time for the Czech Republic in 2001:1-2006:09 estimating various specifications of simple Taylor-type monetary policy rules. First, we estimate it using GMM.
Roman Horváth
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A Note on Optimal Smoothing for Time Varying Coefficient Problems [PDF]

An algorithm is presented which provides a complete solution to the optimal estimation problem for time-varying parameters when no proper prior distribution is specified.
Thomas F. Cooley, Kent D. Wall
core  

The Impact of Tourism Activities on Carbon Emissions: Evidence Using a Time-Varying Parameter Vector Autoregression Model

İktisat Politikası Araştırmaları Dergisi
This article examines the impact of tourism activities, economic growth, and energy demand on environmental degradation in Turkey using Primiceri’s (2005) time-varying parameter structural vector autoregression model for the period 1991:Q1 to 2020:Q1 ...
A. Nazif Çatık, Esra Ballı, Coşkun Akdeniz, Cihan Çobanoğlu, Mohamad Husam Helmi   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

How Does Monetary Policy Change? Evidence on Inflation Targeting Countries [PDF]

We examine the evolution of monetary policy rules in a group of inflation targeting countries (Australia, Canada, New Zealand, Sweden and the United Kingdom) applying moment- based estimator at time-varying parameter model with endogenous regressors ...
Borek Vasícek, Jaromír Baxa, Roman Horváth   +2 more
core   +2 more sources

An integrated framework for non-stationary hydrological drought assessment using time-varying parameter standardized streamflow index and time-varying threshold level method

Journal of Hydrology: Regional Studies
Study region: Weihe River basin (WRB) in northern China. Study focus: In a changing environment, traditional drought assessment methods may not be applicable when assumptions of stationarity are violated. Accordingly, this study proposes a framework that
Menghao Wang, Shanhu Jiang, Liliang Ren, Junzeng Xu, Shanshui Yuan, Chong-Yu Xu   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source