Results 161 to 170 of about 22,781,989 (354)

Rapid equivalent simplification algorithm for complex underground mine ventilation networks

Meitan xuebao
Mine ventilation network equivalent simplification technology is a powerful tool for analyzing fluid networks. However, with the increasing number of tunnels in mine ventilation networks, their complexity also rises, challenging the precision and ...
Jinzhang JIA, Wentian SHANG, Jian LIU, Lijun Deng   +3 more
doaj   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Total Outer-Independent Domination Number: Bounds and Algorithms

Algorithms
In graph theory, the study of domination sets has garnered significant interest due to its applications in network design and analysis. Consider a graph G(V,E); a subset of its vertices is a total dominating set (TDS) if, for each x∈V(G), there exists an
Paul Bosch, Ernesto Parra Inza, Ismael Rios Villamar, José Luis Sánchez-Santiesteban   +3 more
doaj   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

A Concentration-Based Adaptive Approach to Region Mergingof Optimal Time and Space Complexities [PDF]

, 2000
Christophe Fiorio, Richard Nock
openalex   +1 more source

The T-DBSCAN Algorithm for Stopover Site Identification of Migration Birds Based on Satellite Positioning Data

Biology
With the acceleration of social development and urbanization, birds’ natural habitats have been greatly disturbed and threatened. Satellite tracking technology can collect much bird activity data, providing important data support for habitat protection ...
Xinwu He, Xiqun Liu, Jiajia Liu, Youwen Li, Zhenggang Xu, Ping Mo, Tian Huang   +6 more
doaj   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Measuring the complexity of time series: An application to neurophysiological signals [PDF]

, 2000
Sara L. Gonzalez Andino, R. Grave de Peralta Menendez, G. Thut, L. Spinelli, O. Blanke, C.M. Michel, T. Landis   +6 more
openalex   +1 more source