Results 171 to 180 of about 22,397,908 (376)

Knee point search using cascading top-k sorting with minimized time complexity. [PDF]

ScientificWorldJournal, 2013
Wang Z, Tseng SS.
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

On the time-complexity of broadcast in multi-hop radio networks: An exponential gap between determinism and randomization

, 1992
Reuven Bar-Yehuda, Oded Goldreich, Alon Itai   +2 more
openalex   +1 more source

On the Complexity of Scheduling Conditional Real-Time Code [PDF]

, 2001
Samarjit Chakraborty, Thomas Erlebach, Lothar Thiele   +2 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

New related-key rectangle attack on 42-round SHACAL-2

Tongxin xuebao, 2009
A new 34-round related-key rectangle distinguisher was constructed by exploiting the properties of the round transform of SHACAL-2. Moreover, two new relate-key rectangle attacks on 40-round and 42-round reduced SHACAL-2 were presented by using both the ...
WEI Yong-zhuang1, 2
doaj  

Almost-everywhere complexity hierarchies for nondeterministic time

, 1993
Eric Allender, Richard Beigel, Ulrich Hertrampf, Steven Homer   +3 more
openalex   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Low-Complexity Iterative Receiver for Space-Time Coded Signals over Frequency Selective Channels [PDF]

, 2002
Noura Sellami, Inbar Fijalkow, Mohamed Siala   +2 more
openalex   +1 more source