Results 91 to 100 of about 3,283,200 (344)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Effect of Screen Time on Delays in Language and Speech Developmental Children: Meta-Analysis

open access: yesJurnal Ilmu dan Teknologi Kesehatan
Language is a communication tool that humans often use. In the current globalisation era, finding and exchanging information takes effort. This is of course because of progress in the era of globalization, everything has become more accessible and easier
Liza Laela Abida
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A Cumulative-signals-based Method for Time Delay Estimation

open access: yesMeasurement Science Review, 2019
An original method for time delay estimation is presented. It is based on changing input signals into cumulative ones, followed by determination of inflection points of cumulative curves, and estimation of time delay as time difference of these points ...
Mosorov Volodymyr
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dimensional reduction of nonlinear time delay systems

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2005
Whenever there is a time delay in a dynamical system, the study of stability becomes an infinite-dimensional problem. The centre manifold theorem, together with the classical Hopf bifurcation, is the most valuable approach for simplifying the infinite ...
M. S. Fofana
doaj   +1 more source

COSMOGRAIL: the COSmological MOnitoring of GRAvItational Lenses XV. Assessing the achievability and precision of time-delay measurements

open access: yes, 2015
COSMOGRAIL is a long-term photometric monitoring of gravitationally lensed QSOs aimed at implementing Refsdal's time-delay method to measure cosmological parameters, in particular H0. Given long and well sampled light curves of strongly lensed QSOs, time-
Bonvin, V.   +5 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

On the Min-Max-Delay Problem: NP-completeness, Algorithm, and Integrality Gap

open access: yes, 2018
We study a delay-sensitive information flow problem where a source streams information to a sink over a directed graph G(V,E) at a fixed rate R possibly using multiple paths to minimize the maximum end-to-end delay, denoted as the Min-Max-Delay problem ...
Chen, Minghua   +3 more
core   +1 more source

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