Results 71 to 80 of about 1,240,738 (311)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Random Time Delay Effect on Out-of-Sequence Measurements

IEEE Access, 2016
The communication links of multi-agent systems (MASs) generate random time delays, which significantly affect accuracy and real-time control. A Markov chain is established at the input end and output end of a communication link to express this time delay
Zhe Li, Huixiang Zhang, Dejun Mu, Lantian Guo   +3 more
doaj   +1 more source

Time-delay compensator design

2017 11th Asian Control Conference (ASCC), 2017
The problem of designing linear time-invariant stabilizing time-delay compensators for a class of linear timeinvariant retarded time-delay systems is considered. To solve this problem, an approach, based on the continuous pole placement algorithm, is proposed. A design example is also presented to demonstrate the proposed approach.
Erol, H. Ersin, Iftar, Altug
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Effect of Screen Time on Delays in Language and Speech Developmental Children: Meta-Analysis

Jurnal Ilmu dan Teknologi Kesehatan
Language is a communication tool that humans often use. In the current globalisation era, finding and exchanging information takes effort. This is of course because of progress in the era of globalization, everything has become more accessible and easier
Liza Laela Abida
doaj   +1 more source

Delay-dependent exponential stability of neutral stochastic delay systems

, 2009
This paper studies stability of neutral stochastic delay systems by linear matrix inequality (LMI) approach. Delay dependent criterion for exponential stability is presented and numerical examples are conducted to verify the effectiveness of the proposed
Mao, X., Huang, L.
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A Cumulative-signals-based Method for Time Delay Estimation

Measurement Science Review, 2019
An original method for time delay estimation is presented. It is based on changing input signals into cumulative ones, followed by determination of inflection points of cumulative curves, and estimation of time delay as time difference of these points ...
Mosorov Volodymyr
doaj   +1 more source

Delay differential equation models for real-time dynamic substructuring

, 2005
Real-time dynamic substructuring is a testing technique that models an entire system through the combination of an experimental test piece, representing part of the system, with a numerical model of the rest of the system.
Wagg, DJ, Wallace, MI, Neild, SA, Sieber, J, Krauskopf, B   +4 more
core