Results 101 to 110 of about 3,283,200 (344)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Observer‐Based Leader‐Following Consensus of General Linear Multiagent Systems Based on Novel Event Trigger Mechanism with Input Time Delay under Directed Graphs [PDF]
, 2021 Hong Zhang, Changshun Chen, Wei Feng
openalex +1 more source
Radial density profiles of time-delay lensing galaxies
, 2007 We present non-parametric radial mass profiles for ten QSO strong lensing galaxies. Five of the galaxies have profiles close to $\rho(r)\propto r^{-2}$, while the rest are closer to r^{-1}, consistent with an NFW profile.
A. V. Maccio +8 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Time-Delayed Quantum Feedback Control [PDF]
Physical Review Letters, 2015 A theory of time-delayed coherent quantum feedback is developed. More specifically, we consider a quantum system coupled to a bosonic reservoir creating a unidirectional feedback loop. It is shown that the dynamics can be mapped onto a fictitious series of cascaded quantum systems, where the system is driven by past versions of itself.
openaire +3 more sources
Generalized definition of time delay in scattering theory
, 2006 We advocate for the systematic use of a symmetrized definition of time delay in scattering theory. In two-body scattering processes, we show that the symmetrized time delay exists for arbitrary dilated spatial regions symmetric with respect to the origin.
Amrein W. O. +6 more
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Time Delay Estimation Algoritms for Echo Cancellation
Advances in Electrical and Electronic Engineering, 2011 The following case study describes how to eliminate echo in a VoIP network using delay estimation algorithms. It is known that echo with long transmission delays becomes more noticeable to users.
Kirill Sakhnov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source