Results 41 to 50 of about 33,434 (310)
Symmetry, Integrability and Geometry: Methods and Applications, 2011 The original continuous-time "goldfish" dynamical system is characterized by two neat formulas, the first of which provides the $N$ Newtonian equations of motion of this dynamical system, while the second provides the solution of the corresponding initial-value problem.
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Известия высших учебных заведений. Поволжский регион: Физико-математические наукиBackground. The development of numerical methods for solving initial-boundary value problems for partial differential equations remains highly relevant today.
Ruslan V. Zhalnin, Michael S. Nefedov
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
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Open Physics, 2008 Abstract In this paper we discuss the joint propagation of a periodically modulated field and a pulse of different frequency in an optical fiber. The pulse experiences the action of an index lattice induced via cross-phase modulation by the periodic field.
Peschel, Ulf +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
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Time Discretization Techniques
, 2016 The time discretization of hyperbolic partial differential equations is typically the evolution of a system of ordinary differential equations obtained by spatial discretization of the original problem.
Ketcheson, David I., Gottlieb, S.
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The Finite Volume WENO with Lax–Wendroff Scheme for Nonlinear System of Euler Equations
Mathematics, 2018 We develop a Lax–Wendroff scheme on time discretization procedure for finite volume weighted essentially non-oscillatory schemes, which is used to simulate hyperbolic conservation law.
Haoyu Dong, Changna Lu, Hongwei Yang
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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