Results 51 to 60 of about 33,434 (310)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dynamics of Structures with Distributed Gyroscopes: Modal Discretization Versus Spatial Discretization

open access: yesApplied Sciences, 2019
In this study, two discretization numerical methods, modal discretization and spatial discretization methods, were proposed and compared when applied to the gyroscopic structures.
Xiao-Dong Yang   +3 more
doaj   +1 more source

Discrete-time randomized sampling [PDF]

open access: yesICECS 2001. 8th IEEE International Conference on Electronics, Circuits and Systems (Cat. No.01EX483), 2002
This paper explores the use of randomized sampling in implementing convolution in discrete-time with application to the areas of approximate filtering, low-power filter design, and hardware failure modeling. Three distinct randomized sampling methods are presented and additive error models as well as second-order error statistics are derived for these ...
Maya R. Said, Alan V. Oppenheim
openaire   +1 more source

New Stability Tests for Discretized Fractional-Order Systems Using the Al-Alaoui and Tustin Operators

open access: yesComplexity, 2018
This paper provides new results on a stable discretization of commensurate fractional-order continuous-time LTI systems using the Al-Alaoui and Tustin discretization methods.
Rafał Stanisławski   +2 more
doaj   +1 more source

LDG schemes with second order implicit time discretization for a fractional sub-diffusion equation

open access: yesResults in Applied Mathematics, 2019
In this paper, we propose new local discontinuous Galerkin (LDG) schemes for solving a time fractional sub-diffusion equation. The new LDG schemes is constructed rely on the splitting of time fractional derivative and space derivative.
Can Li, Xiaorui Sun, Fengqun Zhao
doaj   +1 more source

An Energy Consistent Discretization of the Nonhydrostatic Equations in Primitive Variables

open access: yesJournal of Advances in Modeling Earth Systems, 2020
We derive a formulation of the nonhydrostatic equations in spherical geometry with a Lorenz staggered vertical discretization. The combination conserves a discrete energy in exact time integration when coupled with a mimetic horizontal discretization ...
Mark A. Taylor   +5 more
doaj   +1 more source

A Discrete-Time State Estimation for Nonlinear Systems With Noises

open access: yesIEEE Access, 2020
This paper proposes a discrete-time observer to estimate states of continuous-time nonlinear systems with presences of noises. Most conventional discrete-time state observers are designed using discrete-time models, which are derived by applying the ...
Triet Nguyen-Van
doaj   +1 more source

Spectral discretization of the time-dependent Navier-Stokes problem with mixed boundary conditions

open access: yesAdvances in Nonlinear Analysis, 2022
In this work, we handle a time-dependent Navier-Stokes problem in dimension three with a mixed boundary conditions. The variational formulation is written considering three independent unknowns: vorticity, velocity, and pressure.
Abdelwahed Mohamed, Chorfi Nejmeddine
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

High-Order Time Discretization of The Wave Equation by Nabla-P Scheme.*

open access: yesESAIM: Proceedings and Surveys, 2014
High-order Discontinuous Galerkin Methods (DGM) are now routinely used for simulation of wave propagation, especially for geophysical applications.
Barucq Hélène   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy