Results 61 to 70 of about 14,490,979 (304)
Open Physics, 2008 Abstract In this paper we discuss the joint propagation of a periodically modulated field and a pulse of different frequency in an optical fiber. The pulse experiences the action of an index lattice induced via cross-phase modulation by the periodic field.
Peschel, Ulf +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
An algorithm for solving the Navier–Stokes problem with mixed boundary conditions
Boundary Value Problems, 2022 We consider a time-dependent Navier–Stokes problem in dimension two and three provided with mixed boundary conditions. We propose an iterative algorithm and its implementation for resolving this considered problem.
Mohamed Abdelwahed +3 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
cAnt-Miner: an ant colony classification algorithm to cope with continuous attributes [PDF]
, 2008 This paper presents an extension to Ant-Miner, named cAnt-Miner (Ant-Miner coping with continuous attributes), which incorporates an entropy-based discretization method in order to cope with continuous attributes during the rule construction process.
Otero, Fernando E.B. +5 more
core +1 more source
Process Algebra with Timing: Real Time and Discrete Time [PDF]
, 2001 We present real time and discrete time versions of ACP with absolute timing and relative timing. The starting-point is a new real time version with absolute timing, called ACPsat, featuring urgent actions and a delay operator. The discrete time versions are conservative extensions of the discrete time versions of ACP being known as ACPdat and ACPdrt ...
Baeten, J.C.M., Middelburg, C.A.
openaire +4 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Digital Resonant Controller based on Modified Tustin Discretization Method
Advances in Electrical and Computer Engineering, 2016 Resonant controllers are used in power converter voltage and current control due to their simplicity and accuracy. However, digital implementation of resonant controllers introduces problems related to zero and pole mapping from the continuous to the ...
STOJIC, D.
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source