Results 161 to 170 of about 36,626,105 (254)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Time-Domain Analysis of Chest Impedance for Venous Air Embolism Detection: An Open-Source Software Tool and Single-Cadaver Pilot Study. [PDF]

Cureus
Marcellino C, Johnston M, Robinson N, Abcejo AS.   +3 more
europepmc   +1 more source

On Time Domain Analysis of Photoplethysmogram Signals for Monitoring Heat Stress. [PDF]

Sensors (Basel), 2015
Elgendi M, Fletcher R, Norton I, Brearley M, Abbott D, Lovell NH, Schuurmans D.   +6 more
europepmc   +1 more source

Under the Clouds of War

, 1972
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Time-Domain Analysis of Low- and High-Frequency Near-Infrared Spectroscopy Sensor Technologies for Characterization of Cerebral Pressure-Flow and Oxygen Delivery Physiology: A Prospective Observational Study. [PDF]

Sensors (Basel)
Sainbhi AS, Vakitbilir N, Bergmann T, Stein KY, Hasan R, Silvaggio N, Hayat M, Moon J, Zeiler FA.   +8 more
europepmc   +1 more source

Time-domain analysis of scrotal thermoregulatory impairment in varicocele. [PDF]

Front Physiol, 2014
Ismail E, Orlando G, Pompa P, Gabrielli D, Di Donato L, Cardone D, Merla A.   +6 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Brillouin expanded time-domain analysis based on dual optical frequency combs. [PDF]

Light Sci Appl
Youn JH, Song KY, Martin-Lopez S, Gonzalez-Herraez M, Fernández-Ruiz MR.   +4 more
europepmc   +1 more source

Frequency and Time Domain Analysis of Foetal Heart Rate Variability with Traditional Indexes: A Critical Survey. [PDF]

Comput Math Methods Med, 2016
Romano M, Iuppariello L, Ponsiglione AM, Improta G, Bifulco P, Cesarelli M.   +5 more
europepmc   +1 more source