Results 141 to 150 of about 5,380,901 (293)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Theoretical Study of Lumped Parameter Circuits and Multiconductor Transmission Lines for Time-Domain Analysis of Electromagnetic Noise. [PDF]

Sci Rep, 2019
Abe M, Toki H.
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Time-domain analysis for extracting fast-paced pupil responses. [PDF]

Sci Rep, 2017
Zénon A.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Bioelectrical Impedance-Based Time-Domain Analysis for Cerebral Autoregulation Assessment. [PDF]

Sensors (Basel)
Zhou Y, He W, Yang B, Shi X, Liu Y, Shi Y, Fu F.   +6 more
europepmc   +1 more source

Discrimination of Temperature and Strain in Brillouin Optical Time Domain Analysis Using a Multicore Optical Fiber. [PDF]

Sensors (Basel), 2018
Zaghloul MAS, Wang M, Milione G, Li MJ, Li S, Huang YK, Wang T, Chen KP.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Heart Rate Variability Time-Domain Analysis Across Glaucoma Subtypes. [PDF]

Biomedicines
Yoshida Y, Takei H, Ukisu M, Takagi K, Tanito M.   +4 more
europepmc   +1 more source

Finite-difference time-domain analysis of increased penetration depth in optical coherence tomography by wavefront shaping. [PDF]

Biomed Opt Express, 2018
Kim JU, Choi H, Park Y, Shin J.
europepmc   +1 more source