Results 71 to 80 of about 18,589,267 (236)

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

Bridging Anatomy Curricular Gaps: Leveraging Student‐Created Video Resources in Elective Courses

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Traditional anatomical donor‐based dissection has long served as the cornerstone of anatomical education. However, with increasingly condensed curricula and diverse student learning preferences, multimedia tools have become vital adjuncts to support engagement, comprehension, and accessibility. At the Carle Illinois College of Medicine (CI MED)
Megan A. Lim   +2 more
wiley   +1 more source

Virtual Reality in Medical Education: A Concept Analysis

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Virtual reality (VR) remains inconsistently defined in medical education, with the term being applied to heterogeneous immersive and nonimmersive technologies. This inconsistency may hinder intervention classification, evidence synthesis, curriculum planning, and technology selection.
Arthur Rodrigues Lima   +7 more
wiley   +1 more source

Dynamic Capabilities for Real‐Time Customer Segmentation: Insights From a Sequential Mixed‐Methods Study

open access: yesJournal of Consumer Behaviour, EarlyView.
ABSTRACT Conventional approaches to customer segmentation, static and retrospective by nature, fail to adequately capture rapid consumer shifts in dynamic market environments. Drawing from dynamic capabilities theory, this article reconceptualizes segmentation as an adaptive, capability‐driven practice rather than as a passive classification exercise ...
Subhajit Pahari   +4 more
wiley   +1 more source

Application of Four Frailty Assessment Tools in Elderly Patients With Coronary Heart Disease PCI and Its Relationship With Quality of Life

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Frailty is highly prevalent among elderly patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI) and is associated with adverse clinical outcomes and impaired health‐related quality of life.
Meixun Huang   +5 more
wiley   +1 more source

Determination and Recovery of Spin‐States for a High‐Spin and a Spin‐Crossover Complex by Means of X‐Ray Wavefunction Refinement

open access: yesChemistry – A European Journal, EarlyView.
The determination of spin‐states by methods like Hirshfeld atom refinement is a promising development in the field of quantum crystallography. To this end, we present x‐ray wavefunction refinement as a next step in this process, identifying the spin and translating it into a physical wavefunction.
Johannes Bartusel   +3 more
wiley   +1 more source

Captivated by Kinesin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
wiley   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho   +12 more
wiley   +1 more source

Evidence for functional convergence between LZTS2 and DYRK1A during craniofacial development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Precise control of DYRK1A dosage is essential for embryonic development, including craniofacial morphogenesis. While LZTS2 is among the most consistently identified DYRK1A‐interacting proteins, its roles in embryonic development remain incompletely understood, and its potential contribution to craniofacial development has not been ...
Nicole Cheng   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy